Related Experiment Video

Updated: Dec 14, 2025

A Phenotyping Regimen for Genetically Modified Mice Used to Study Genes Implicated in Human Diseases of Aging
09:37

A Phenotyping Regimen for Genetically Modified Mice Used to Study Genes Implicated in Human Diseases of Aging

Published on: July 14, 2016

8.6K

Genetic associations for two biological age measures point to distinct aging phenotypes

Chia-Ling Kuo, Luke C Pilling, Zuyun Liu

    Medrxiv : the Preprint Server for Health Sciences
    |July 18, 2020
    PubMed

    More Related Videos

    Automated Analysis of C. elegans Swim Behavior Using CeleST Software08:47

    Automated Analysis of C. elegans Swim Behavior Using CeleST Software

    Published on: December 7, 2016

    13.2K
    Surveying Low-Cost Methods to Measure Lifespan and Healthspan in Caenorhabditis elegans10:08

    Surveying Low-Cost Methods to Measure Lifespan and Healthspan in Caenorhabditis elegans

    Published on: May 18, 2022

    3.8K

    Related Concept Videos

    Aging01:26

    Aging

    Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
    Cellular Clock Theory
    The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
    490
    Pharmacodynamics in Geriatric Patients: Effects of Age01:27

    Pharmacodynamics in Geriatric Patients: Effects of Age

    Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
    125
    The Effect of Aging on Tissues01:19

    The Effect of Aging on Tissues

    Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
    3.1K
    Background and Environment Affect Phenotype02:27

    Background and Environment Affect Phenotype

    Although the genetic makeup of an organism plays a major role in determining the phenotype, there are also several environmental factors, such as temperature, oxygen availability, presence of mutagens, that can alter an organism’s phenotype.
    An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
    7.2K
    Human Genetics01:28

    Human Genetics

    Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
    The complex relationship between genetics and psychology is observable through common biological components such...
    1.3K
    Gene-Environment Interactions01:20

    Gene-Environment Interactions

    Gene expression is a dynamic process that is significantly influenced by environmental factors. This interaction underlies the complex nature of biological development and the phenotypic differences observed among individuals, even among those with identical genetic makeups. Factors such as radiation, temperature, behavior, nutrition, and stress play pivotal roles in determining how genes are expressed. The concept of the reaction range is central to understanding this interaction. It posits...
    938