[Neonatal adrenal hemorrhage in the context of isoimmune neonatal jaundice. Case report]
Related Experiment Video
Updated: Dec 14, 2025

Isolation of Neonatal Extrahepatic Cholangiocytes
Published on: June 5, 2014
Cristina Arribas Sánchez1, Cristina Menéndez Hernando2, Marta Gambra Arzoz2
1Clínica Universidad de Navarra, Madrid (España). carribass@unav.es.
Abstract:
Hemorrhage of the adrenal glands in the neonatal period happens secondarily to birth trauma and to changes in venous pressure. Neonatal jaundice has as an infrequent etiology the presence of an adrenal gland hematoma. Symptomatic cases are rare, and if they manifest, it is usually as prolonged jaundice. We present the case of a neonate who was admitted at 20 hours of life due to isoimmune jaundice. Due to an increase in conjugatedbi]irubin, an abdominal ultrasound was requested at 10 days of life, which showed a non-vascularized right adrenal mass, 50 x 21 mm, with cystic images inside, compatible with bleeding of the right adrenal gland. Serial ultrasound showed a progressive resolution until its disappearance, keeping the baby asymptomatic and withoutj aundice. In cases of prolonged jaundice in the neonatal period, the possibility of significant adrenal hemorrhage must be assessed.

