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The immunoregulatory function of polyphenols: implications in cancer immunity
José Tarcísio Giffoni de Carvalho1, Debora Da Silva Baldivia1, David Tsuyoshi Hiramatsu de Castro1
1Research Group on Biotechnology and Bioprospecting Applied to Metabolism, Federal University of Grande Dourados, Dourados, Brazil.
Abstract:
Polyphenols have demonstrated several potential biological activities, notably antitumoral activity dependent on immune function. In the present review, we describe studies that investigated antitumor immune responses influenced by polyphenols and the mechanisms by which polyphenols improve the immune response. We also discuss the limitations in related areas, especially unexplored areas of research, and next steps required to develop a therapeutic approach utilizing polyphenols in oncology.
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