Nanopatterning proteins and peptides
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Updated: Dec 14, 2025

Ligand Nano-cluster Arrays in a Supported Lipid Bilayer
Published on: April 23, 2017
Karen L Christman1, Vanessa D Enriquez-Rios2, Heather D Maynard1
1Department of Chemistry and Biochemistry, 607 Charles E. Young Drive East, Los Angles, CA 90095-1569 and California NanoSystems Institute, University of California Los Angeles, 6722 Boelter Hall, Los Angles, CA 90095-7151. maynard@chem.ucla.edu.
Abstract:
A variety of techniques have been developed to site-specifically immobilize biomolecules onto surfaces with resolutions below one micron. The ability to pattern proteins and peptides in particular has great potential for applications in biosensors, biomaterials, and tissue engineering. For example, immobilizing proteins at the nanoscale could lead to the development of diagnostic protein nanoarrays, while patterning peptides could lead to greater control over the cell/biomaterial interface. This review discusses the methods that have been reported for patterning proteins and peptides with submicron and nanometer resolutions.

