Thermally-induced glass formation from hydrogel nanoparticles
D Missirlis1, J A Hubbell1, N Tirelli2
1Department of Materials and Institute of Biomedical Engineering, ETH Zurich and the University of Zurich, Moussonstrasse 18, CH-8044, Zurich, Switzerland. dimitrios.misirlis@epfl.ch and Integrative Biosciences Institute, Swiss Federal Institute of Technology Lausanne (EPFL), CH-1015, Lausanne, Switzerland. jeffrey.hubbell@epfl.ch.
Abstract:
Amphiphilic hydrogel nanoparticles, composed of covalently cross-linked Pluronic F127 and PEG, exhibit a temperature- and concentration-dependent gelation in water which is interpreted as a colloidal glass formation. The possible applications of these phenomena in biomaterials and controlled release are also discussed.
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