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Anogenital Distance and Perineal Measurements of the Pelvic Organ Prolapse POP Quantification System
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Global Gender Differences in Pilonidal Sinus Disease: A Random-Effects Meta-Analysis.

Markus M Luedi1, Patrick Schober2, Verena K Stauffer3

  • 1Department of Anaesthesiology and Pain Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.

World Journal of Surgery
|July 19, 2020
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Summary
This summary is machine-generated.

Pilonidal sinus disease (PSD) affects a considerable number of women globally, challenging the notion of it being exclusively a male condition. Significant regional variations exist in female PSD prevalence, warranting further investigation.

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Area of Science:

  • Medical research
  • Epidemiology
  • Surgical pathology

Background:

  • Pilonidal sinus disease (PSD) is traditionally perceived as predominantly affecting young males.
  • Changing lifestyles in developed nations may influence PSD demographics.
  • The study questions the uniform distribution and male-centric view of PSD incidence worldwide.

Purpose of the Study:

  • To investigate the global prevalence of pilonidal sinus disease (PSD) in female patients.
  • To determine if PSD distribution is homogenous across different world regions.
  • To challenge the traditional view of PSD as an overwhelmingly male disease.

Main Methods:

  • A comprehensive meta-analysis of world literature from 1833 to 2018 was conducted.
  • Data from an existing database was expanded and analyzed.
  • Random-effects meta-analysis was employed, with adjustments for gender bias in study selection.

Main Results:

  • Female patients constitute 21% of the global pilonidal sinus disease (PSD) cases analyzed.
  • Significant regional disparities in female PSD prevalence were identified: South America (39%), North America/Australia/New Zealand (29%), and Asia (7%).
  • These regional differences remained significant even when gender bias corrections were not applied.

Conclusions:

  • The proportion of female patients with pilonidal sinus disease (PSD) is substantial.
  • Pilonidal sinus disease should be recognized as affecting both men and women.
  • Significant, unexplained regional variations in female PSD prevalence exist globally.