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Updated: Dec 14, 2025

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Characterization of MLKL-mediated Plasma Membrane Rupture in Necroptosis
Published on: August 7, 2018
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Necrobiosis lipoidica with rapid response to doxycycline
Emily Burns1, Uzoamaka Ukoha2, Audrey Chan2,3
1Baylor College of Medicine, Houston, TX, USA.
Pediatric Dermatology
|July 19, 2020
Abstract:
Necrobiosis lipoidica (NL) is a rare granulomatous disease of unknown etiology. Multiple therapies may be used with varying efficacy. We report a pediatric patient with a history of type I diabetes mellitus and NL with minimal response to an ultrapotent topical steroid, topical calcineurin inhibitor, and intralesional triamcinolone, complicated by steroid atrophy, who rapidly responded after addition of doxycycline.

