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Updated: Dec 14, 2025

Pulse Wave Velocity Testing in the Baltimore Longitudinal Study of Aging
Published on: February 7, 2014
Brachial-ankle pulse wave velocity with a custom device.
C Sánchez Bacaicoa1, S Rico-Martín2, E Morales3
1Hospital 12 de Octubre, Universidad Complutense de Madrid, Madrid, España.
The abiPWV device accurately measures brachial-ankle pulse wave velocity (baPWV), a key indicator of arterial stiffness. This validated method offers clinical utility comparable to reference devices for vascular risk assessment.
Area of Science:
- Cardiovascular Research
- Vascular Physiology
- Medical Device Technology
Background:
- Arterial stiffness, assessed by brachial-ankle pulse wave velocity (baPWV), is crucial for vascular risk evaluation.
- The abiPWV device measures various pulse wave velocities (PWVs) and the ankle-brachial index (ABI).
Purpose of the Study:
- To calculate baPWV using the abiPWV device.
- To validate abiPWV-derived baPWV against a reference device (VaSera).
- To investigate the clinical usefulness of abiPWV for arterial stiffness assessment.
Main Methods:
- 113 patients (mean age 53±12 years, 52% women) were studied.
- Participants were stratified by cardiovascular risk factors (CRFs) into three groups.
- baPWV was measured concurrently using both abiPWV and VaSera devices.
Main Results:
- A high correlation (r=0.93, P<.001) was found between abiPWV and VaSera for baPWV.
- The percentage error was 4.5% via Bland-Altman analysis, indicating good agreement.
- Significant increases in baPWV were observed with increasing CRFs, comparable between devices.
Conclusions:
- The abiPWV device provides a safe and reliable measurement of baPWV.
- Its clinical utility for assessing arterial stiffness is comparable to the reference VaSera device.
- The integration of baPWV measurement enhances the abiPWV's capability as a comprehensive vascular assessment tool.
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