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Pathogenesis and management of myocardial injury in coronavirus disease 2019

Zhi-Yao Wei1, Yong-Jian Geng2, Ji Huang3

  • 1Center for Coronary Heart Disease, Department of Cardiology, Fu Wai Hospital, National Center for Cardiovascular Diseases of China, State Key Laboratory of Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

European Journal of Heart Failure
|July 20, 2020
PubMed

Insights

Coronavirus disease 2019 (COVID-19) poses significant cardiovascular risks, especially for older adults. This review details COVID-19

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Public Health

Background:

  • Coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, is a global pandemic.
  • COVID-19 presents with high infectivity and diverse clinical symptoms.
  • Cardiovascular complications, including myocardial injury, are noted in COVID-19 patients, particularly the elderly.

Purpose of the Study:

  • To review the epidemiology of COVID-19.
  • To explore the mechanisms behind COVID-19 cardiovascular complications.
  • To summarize clinical manifestations and management strategies for these complications.

Main Methods:

  • Literature review of epidemiological data.
  • Analysis of studies on COVID-19 pathophysiology.
  • Synthesis of clinical case reports and management guidelines.

Main Results:

  • COVID-19 exhibits rapid global spread and varied clinical presentations.
  • Mechanisms linking SARS-CoV-2 infection to cardiac injury are multifaceted.
  • Management strategies are evolving, focusing on supportive care and addressing specific cardiovascular issues.

Conclusions:

  • COVID-19 significantly impacts cardiovascular health, necessitating focused clinical attention.
  • Understanding the cardiovascular implications of COVID-19 is crucial for patient outcomes.
  • Further research is needed to refine treatment protocols for COVID-19-related cardiac conditions.

Keywords:
Blood vesselsCOVID-19HeartInflammationSARS-CoV-2

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