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Overview of management of children with COVID-19

Dyah Kanya Wati1, Arya Krisna Manggala2

  • 1Pediatric Emergency and Intensive Care Sanglah Public Hospital, School of Medicine, Udayana University, Denpasar, Bali, Indonesia.

Clinical and Experimental Pediatrics
|July 21, 2020
PubMed

Insights

Exploring potential COVID-19 treatments for children is crucial, as management strategies remain inconclusive. This review examines various modalities, including mechanical ventilation and antivirals, for severe pediatric cases.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Virology

Background:

  • Coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, presents a significant global health challenge.
  • Pediatric COVID-19 cases often exhibit milder symptoms compared to adults.
  • Current understanding of COVID-19 pathogenesis and effective management in children is still evolving.

Purpose of the Study:

  • To explore potential treatment modalities for COVID-19 in pediatric populations.
  • To review existing evidence from case reports, guidelines, and review articles on pediatric COVID-19 management.
  • To identify promising therapeutic options for severe COVID-19 cases in children.

Main Methods:

  • Literature review of case reports, review articles, and clinical guidelines.
  • Analysis of potential treatment strategies for COVID-19 in children.
  • Focus on symptomatic and respiratory support measures.

Main Results:

  • Several treatment options show promise for reducing COVID-19 symptoms in severe pediatric cases.
  • Modalities discussed include mechanical ventilation (MV), antiviral drugs, and immune-modulating agents.
  • No randomized clinical trials specifically for pediatric COVID-19 treatments have been published yet.

Conclusions:

  • Further research is needed to establish definitive treatment protocols for pediatric COVID-19.
  • Exploring various therapeutic avenues is essential given the ongoing impact of the pandemic.
  • Current management relies on symptomatic care and supportive interventions, with emerging evidence for specific agents.

Keywords:
COVID-19ChildTreatment

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