Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Chronic Kidney Disease II: Clinical Manifestations01:24

Chronic Kidney Disease II: Clinical Manifestations

434
Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
434
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

247
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
247
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

791
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
791
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

306
The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
306
Disorders of Hemostasis01:24

Disorders of Hemostasis

1.7K
Hemostasis, the process that stops bleeding after a blood vessel injury, is crucial for maintaining the integrity of the circulatory system. However, disorders of hemostasis can disrupt this delicate balance, leading to either excessive clotting or bleeding. These disorders can be broadly classified into thromboembolic disorders and bleeding disorders.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
1.7K
Chronic Kidney Disease I: Introduction01:25

Chronic Kidney Disease I: Introduction

437
Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
437

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Chemical profiling and evaluation of in vitro antibacterial and antibiotic synergistic activities of Cleistanthus bracteosus Jabl. from Malaysian rainforests.

BMC complementary medicine and therapies·2026
Same author

Bergenin attenuates neuropathic pain by modulation of TRPV1/CGRP signalling and neuro-inflammatory mechanisms.

Molecular biology reports·2026
Same author

TIM-3 as an immune and leukemia stem-cell biomarker in acute myeloid leukemia: diagnostic laboratory and translational perspectives.

Clinica chimica acta; international journal of clinical chemistry·2026
Same author

FLT3 mutations as diagnostic and prognostic biomarkers in acute myeloid leukemia.

Clinica chimica acta; international journal of clinical chemistry·2026
Same author

Calreticulin mutations in essential thrombocythemia and primary myelofibrosis.

Clinica chimica acta; international journal of clinical chemistry·2026
Same author

Enhancing the therapeutic efficacy of curcumin in topical applications through nanoformulations.

Natural product research·2026
Same journal

A randomized controlled trial comparing transforaminal injections of Platelet-rich plasma versus steroid for lumbar herniated disc.

Journal of clinical orthopaedics and trauma·2026
Same journal

Guideline-concordant cefazolin prophylaxis in penicillin allergy labeled arthroplasty patients: Progress and persistent barriers.

Journal of clinical orthopaedics and trauma·2026
Same journal

Association of preoperative modified frailty Index-5 with 30-day mortality and complications in elderly hip fracture surgery: A prospective observational study.

Journal of clinical orthopaedics and trauma·2026
Same journal

Haemorrhage control and definitive fixation strategies in unstable pelvic ring fractures: Integrating damage control and endovascular techniques A narrative review.

Journal of clinical orthopaedics and trauma·2026
Same journal

Dual mobility versus fixed bearings in complex primary total hip arthroplasty: A systematic review and meta-analysis.

Journal of clinical orthopaedics and trauma·2026
Same journal

What can be learned from 90 years of published literature on anterior-inferior hip dislocations in pediatrics?

Journal of clinical orthopaedics and trauma·2026
See all related articles

Related Experiment Video

Updated: Dec 14, 2025

Identifying Dysregulated Genes Induced by Kaposi's Sarcoma-associated Herpesvirus KSHV
07:02

Identifying Dysregulated Genes Induced by Kaposi's Sarcoma-associated Herpesvirus KSHV

Published on: September 14, 2010

13.0K

Kienböck's disease: Where do we stand?

Mohammed Tahir Ansari1, Deepak Chouhan1, Vikas Gupta2

  • 1Department of Orthopaedics, All India Institute of Medical Sciences, New Delhi, India.

Journal of Clinical Orthopaedics and Trauma
|July 21, 2020
PubMed
Summary
This summary is machine-generated.

Kienböck's disease, or avascular necrosis of the lunate, can cause wrist collapse. Newer classifications and advanced treatments show promise for early-stage osteonecrosis management.

Keywords:
Avascular necrosisKienböckLunateSemilunar

More Related Videos

Calcification of Vascular Smooth Muscle Cells and Imaging of Aortic Calcification and Inflammation
08:43

Calcification of Vascular Smooth Muscle Cells and Imaging of Aortic Calcification and Inflammation

Published on: May 31, 2016

20.0K
An In Vitro Model for the Study of Cellular Pathophysiology in Globoid Cell Leukodystrophy
07:45

An In Vitro Model for the Study of Cellular Pathophysiology in Globoid Cell Leukodystrophy

Published on: October 21, 2014

8.3K

Related Experiment Videos

Last Updated: Dec 14, 2025

Identifying Dysregulated Genes Induced by Kaposi's Sarcoma-associated Herpesvirus KSHV
07:02

Identifying Dysregulated Genes Induced by Kaposi's Sarcoma-associated Herpesvirus KSHV

Published on: September 14, 2010

13.0K
Calcification of Vascular Smooth Muscle Cells and Imaging of Aortic Calcification and Inflammation
08:43

Calcification of Vascular Smooth Muscle Cells and Imaging of Aortic Calcification and Inflammation

Published on: May 31, 2016

20.0K
An In Vitro Model for the Study of Cellular Pathophysiology in Globoid Cell Leukodystrophy
07:45

An In Vitro Model for the Study of Cellular Pathophysiology in Globoid Cell Leukodystrophy

Published on: October 21, 2014

8.3K

Area of Science:

  • Orthopedics
  • Hand Surgery
  • Radiology

Background:

  • Kienböck's disease is lunate avascular necrosis, potentially leading to carpal instability and surgical intervention.
  • Exact etiology remains unknown, but mechanical, vascular, and genetic factors are implicated.
  • Traditional understanding necessitates updates with advanced diagnostic and therapeutic modalities.

Purpose of the Study:

  • To provide an updated review on the etiopathogenesis of Kienböck's disease.
  • To discuss recent advancements in disease classification using MRI and arthroscopy.
  • To summarize current and emerging treatment strategies for osteonecrosis of the lunate.

Main Methods:

  • Literature review focusing on recent advancements in Kienböck's disease.
  • Analysis of new classification systems based on arthroscopic and MRI findings.
  • Evaluation of outcomes from recently reported treatment options for lunate osteonecrosis.

Main Results:

  • Advanced imaging and arthroscopy facilitate a better understanding and earlier diagnosis of Kienböck's disease.
  • Emerging treatments demonstrate positive results, particularly in the early stages of osteonecrosis.
  • Updated classification systems aid in tailoring treatment approaches.

Conclusions:

  • Early diagnosis and intervention are crucial for managing Kienböck's disease.
  • Recent literature supports the efficacy of advanced treatment options for lunate osteonecrosis.
  • Continued research into etiopathogenesis and treatment is warranted for improved patient outcomes.