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Renal mycetomas in a 10-month-old female infant without immunodeficiency
Anastasia Gkampeta1, Maria Stamou1, Charalampos Antachopoulos2
12 Pediatric Department, Aristotle University of Thessaloniki, AHEPA Hospital, Thessaloniki, Greece.
Abstract:
Candida albicans is the most prevalent and pathogenic fungal infection of the urinary tract. Although fungal urinary tract infections occur less frequently than bacterial infections, their incidence has increased during the last decades. Prematurity, parenteral nutrition, corticosteroids, immunosuppressive factors, surgical procedures, and prolonged antibiotic therapy are common predisposing factors. We report a case of candidal renal mycetomas in a 10-month-old female infant without immunodeficiency who developed candidal infection after surgical treatment for bilateral vesico-ureteric reflux. The renal candidiasis was treated successfully with fluconazole and echinocandin. The occurrence of mycetomas or fungus balls in patients who are immunocompetent is extremely rare. To the best of our knowledge, this is the second case report of mycetomas occurring in immunocompetent pediatric patients.
Insights
This study details a rare case of renal mycetomas caused by Candida albicans in an immunocompetent infant. Successful treatment with fluconazole and echinocandin highlights effective antifungal strategies for urinary tract infections.
Area of Science:
- Urology
- Mycology
- Infectious Diseases
Background:
- Fungal urinary tract infections (UTIs), primarily caused by Candida albicans, are increasing.
- Common predisposing factors include prematurity, parenteral nutrition, immunosuppression, and prolonged antibiotic use.
- Candidal renal mycetomas are exceptionally rare, particularly in immunocompetent individuals.
Observation:
- A 10-month-old infant without immunodeficiency developed candidal renal mycetomas post-surgery for bilateral vesico-ureteric reflux.
- This case represents a rare instance of fungal ball formation in the kidneys of an immunocompetent pediatric patient.
Findings:
- The infant's renal candidiasis was successfully treated with a combination of fluconazole and echinocandin.
- This case highlights the successful management of a rare fungal infection in a pediatric patient.
Implications:
- The successful treatment of this immunocompetent pediatric patient suggests that aggressive antifungal therapy can be effective even in rare presentations of candidal renal mycetomas.
- This case contributes to the limited literature on fungal ball formation in the urinary tract of immunocompetent children, emphasizing the need for vigilance and prompt treatment.
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