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Updated: Dec 14, 2025

Using Whole Mount in situ Hybridization to Link Molecular and Organismal Biology
Published on: March 31, 2011
Similarities in biological processes can be used to bridge ecology and molecular biology
Johan Hallin1,2,3,4,5, Angel F Cisneros1,2,3,4,5, Mathieu Hénault1,2,3,4,5
1Département de biochimie de microbiologie et de bio-informatique Faculté des sciences et de génie Université Laval Québec Canada.
Abstract:
Much of the research in biology aims to understand the origin of diversity. Naturally, ecological diversity was the first object of study, but we now have the necessary tools to probe diversity at molecular scales. The inherent differences in how we study diversity at different scales caused the disciplines of biology to be organized around these levels, from molecular biology to ecology. Here, we illustrate that there are key properties of each scale that emerge from the interactions of simpler components and that these properties are often shared across different levels of organization. This means that ideas from one level of organization can be an inspiration for novel hypotheses to study phenomena at another level. We illustrate this concept with examples of events at the molecular level that have analogs at the organismal or ecological level and vice versa. Through these examples, we illustrate that biological processes at different organization levels are governed by general rules. The study of the same phenomena at different scales could enrich our work through a multidisciplinary approach, which should be a staple in the training of future scientists.
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