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Apolipoprotein E expression pattern in human induced pluripotent stem cells during in vitro neural induction

Hyunah Lee1, Paulina Nowosiad1, Lucia M Dutan Polit1

  • 1Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, SE5 9NU, UK.

F1000Research
|August 29, 2020
PubMed
Summary

Apolipoprotein E (APOE) expression decreases during human neural stem cell differentiation. This suggests APOE may be crucial for maintaining human neural stem cells, warranting further study.

Keywords:
Apolipoprotein EDirected differentiationInduced pluripotent stem cellsNeural stem cells

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