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Updated: Dec 14, 2025

Author Spotlight: Investigating the Effectiveness of Tuina Therapy for Frozen Shoulder
Published on: July 21, 2023
Bee Venom Acupuncture for Shoulder Pain: A Systematic Review and Meta-analysis of Randomized Controlled Trials
Lei Shen1, Jong Ha Lee2, Jong Cheon Joo1
1Department of Constitutional Medicine, College of Korean Medicine, Wonkwang University, Iksan 54538, Republic of Korea.
Objectives:
Our review aimed to summarize and evaluate evidence on the effectiveness of bee venom acupuncture (BVA) in the treatment of shoulder pain.
Methods:
Randomized controlled trials (RCTs) evaluating the effectiveness of BVA on shoulder pain were searched up to October 2019 in 11 electronic databases (Medline, Embase, CENTRAL, CiNii, CNKI, VIP, Wanfang, Kmbase, NDSL, RISS, OASIS). The methodological quality of the included RCTs were evaluated using Cochrane Risk of Bias tool and a meta-analysis was performed.
Results:
Seven studies were included in the review, and four studies were included in the meta-analysis. Comparing BVA plus conventional therapy (CT) with saline injection plus CT, it showed an effect in favor of BVA plus CT in visual analog scale (VAS) and pain rating scale (PRS) (p = 0.02, p = 0.009, respectively). Comparing BVA plus physiotherapy (PT) with saline injection plus PT, it showed that there was no significant difference in VAS and verbal rating scale (VRS) between the two groups.
Conclusion:
This systematic review and meta-analysis suggest that BVA could be beneficial as an adjuvant treatment for shoulder pain.

