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Effect of Phototherapy on Stroke Volume in Newborn Infants with Jaundice

Majid Firouzi1, Hamidreza Sherkatolabbasieh1, Alireza Nezami1

  • 1Department of Pediatrics, Faculty of Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran.

Journal of Pediatric Intensive Care
|July 21, 2020
PubMed

Insights

Phototherapy for infant jaundice may decrease cardiac output by reducing stroke volume. This study found a significant reduction in left ejection fraction after phototherapy treatment in newborns.

Area of Science:

  • Neonatal Medicine
  • Pediatric Cardiology
  • Medical Imaging

Background:

  • Phototherapy is a common treatment for neonatal hyperbilirubinemia.
  • A rare complication of phototherapy involves altered cardiac output due to blood flow redistribution.
  • The impact of phototherapy on left ejection fraction in infants requires further investigation.

Purpose of the Study:

  • To evaluate the effects of phototherapy on left ejection fraction in infants diagnosed with jaundice.
  • To assess changes in cardiac output parameters following phototherapy treatment.

Main Methods:

  • Twenty-nine infants with jaundice receiving phototherapy were enrolled.
  • Echocardiography was performed immediately before and 24 hours after phototherapy.
  • Stroke volume and left ejection fraction were measured and compared.

Main Results:

  • A statistically significant decrease in stroke volume was observed after phototherapy (p=0.011).
  • Nineteen out of twenty-nine infants showed a reduction in stroke volume post-treatment.
  • The mean stroke volume decreased from 6.99 ± 2.17 to 6.55 ± 1.85 L/m².

Conclusions:

  • Phototherapy may reduce left ejection fraction in newborn infants with hyperbilirubinemia.
  • The findings suggest a potential impact of phototherapy on infant cardiac function.
  • Further research is warranted to understand the clinical significance of these hemodynamic changes.

Keywords:
echocardiographynewbornphototherapystroke volume

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