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Related Concept Videos

Endocarditis I: Introduction01:25

Endocarditis I: Introduction

277
Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
277
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

247
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
247
Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

134
Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
134
Endocarditis IV: Nursing Management01:29

Endocarditis IV: Nursing Management

211
Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
211
Mitral Stenosis I: Introduction01:22

Mitral Stenosis I: Introduction

232
Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
232
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

404
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
404

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Updated: Dec 14, 2025

Isolation of Valvular Endothelial Cells
11:04

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Isolated Pulmonary Valve Endocarditis.

Sudeep Acharya1, Shamsuddin Anwar1, Michael Iannuzzi1

  • 1Internal Medicine, Staten Island University Hospital, Northwell Health, Staten Island, USA.

Cureus
|July 21, 2020
PubMed
Summary
This summary is machine-generated.

Isolated pulmonary valve endocarditis (PVE) is rare, often linked to IV drug use. This case details successful antibiotic treatment for PVE in a patient with end-stage renal disease, highlighting management challenges.

Keywords:
bacteremiaclinical infectious medicineendocarditispulmonary diseasepulmonary valve

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Area of Science:

  • Cardiology
  • Infectious Diseases
  • Nephrology

Background:

  • Right-sided infective endocarditis (IE) commonly affects the tricuspid valve, often associated with intravenous drug abuse or indwelling catheters.
  • Isolated pulmonary valve endocarditis (PVE) is an exceptionally rare clinical presentation of IE.

Observation:

  • A young woman with end-stage renal disease (ESRD) on hemodialysis presented with persistent coagulase-negative Staphylococcus epidermidis (CoNS) bacteremia despite vancomycin treatment.
  • Transesophageal echocardiography revealed a 1.8 cm vegetation on the pulmonary valve, confirming PVE.

Findings:

  • The patient received a six-week course of intravenous daptomycin, leading to successful treatment of the PVE and resolution of bacteremia.
  • Coagulase-negative Staphylococcus epidermidis was identified as the causative pathogen.

Implications:

  • This case underscores the rarity of PVE and presents a successful medical management strategy.
  • The decision-making process between medical and surgical intervention for PVE can be challenging due to limited robust guidelines.