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Double Vision: Isolated Third Cranial Nerve Palsy After Cardiac Catheterization
Mohammad H Jilani1, Hameed Iqbal2, Syed Huda3
1Internal Medicine, State University of New York Upstate Medical University, Syracuse, USA.
Insights
A rare neurological complication, third cranial nerve palsy, can occur after cardiac catheterization. Prompt recognition and neuroimaging are crucial for managing this vision-impairing condition.
Area of Science:
- Neurology
- Ophthalmology
- Cardiology
Background:
- Cardiac catheterization is a common procedure for diagnosing and treating coronary artery disease (CAD).
- Neurological complications, though rare, can significantly impact patient outcomes.
- Third cranial nerve palsy (oculomotor nerve palsy) affects eye movement and eyelid control.
Observation:
- A 72-year-old male with diabetes mellitus and CAD developed isolated left third cranial nerve palsy two hours post-cardiac catheterization.
- Symptoms included new-onset double vision, left eyelid ptosis, sluggish pupillary reflex, and impaired eye adduction.
- Neurological examination and neuroimaging (CT angiogram, MRI brain) were unremarkable.
Findings:
- The case highlights an unusual neuro-ophthalmologic complication following a cardiac procedure.
- Embolic phenomena are a suspected mechanism, potentially causing small vessel ischemia or microinfarction.
- The presentation was consistent with isolated oculomotor nerve dysfunction.
Implications:
- Prompt recognition and neuroimaging are essential for diagnosing post-cardiac catheterization neurological events.
- Management includes antiplatelet therapy (aspirin), statins, and ophthalmologic evaluation for symptomatic management (e.g., prism lenses).
- This case underscores the importance of considering rare but serious complications in patients undergoing cardiovascular interventions.
Abstract:
Neurological complications after cardiac catheterization are rare. We report an unusual case of isolated third cranial nerve palsy in a 72-year-old male patient whose past medical history was significant for diabetes mellitus and coronary artery disease (CAD). He presented for elective cardiac catheterization for stable angina, which revealed multivessel CAD and no intervention was done. Two hours after the procedure, the patient suddenly started complaining of new-onset double vision in his left eye. Ophthalmologic exam revealed ptosis of the left eye lid, sluggish pupillary reflex and impaired adduction of the left eye along with exotropia of the left eye on primary gaze, all findings consistent with the left third nerve palsy. Rest of the neurological exam and neuroimaging (CT angiogram of head and MRI brain) were normal. Embolic phenomenon has been described as a possible mechanism in such patients leading to small vessel ischemic disease and cerebral microinfarction. Neuro-ophthalmologic complications after cardiac catheterization are rare but devastating for the patients. These should be recognized promptly, and patients should undergo neuroimaging to evaluate for any identifiable causes. These patients should be treated with aspirin and statin therapy and evaluated by ophthalmology for correction with prism lenses if symptoms persist.
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