Related Experiment Video
Updated: Dec 14, 2025

Humanized Mouse Model to Study Bacterial Infections Targeting the Microvasculature
Published on: April 1, 2014
Neisseria meningitidis pneumonia with bacteremia without meningitis: An atypical presentation
Fatma Mohamed Mahmoud1, Thana Harhara1
1Sheikh Khalifa Medical City, Abu Dhabi, United Arab Emirates.
Abstract:
Neisseria meningitidis remains the most important cause of bacterial meningitis worldwide. The second most common and potentially severe end-organ manifestation of invasive meningococcal disease is meningococcal pneumonia. It occurs between 5 % and 15 % of all patients with invasive meningococcal disease. N. meningitidis sepsis and meningitis continue to be associated with high morbidity and mortality, however, meningococcal pneumonia is uncommon and often underreported. We describe a case of sepsis secondary to pneumonia with N. meningitidis bacteremia, without any evidence of meningitis. This case reports aims at highlighting pneumonia as a presentation of N. meningitidis bacteremia, and the need for a high level of clinical suspicion to establish the diagnosis.
Insights
Neisseria meningitidis can cause pneumonia, a less common but severe manifestation of meningococcal disease. This case highlights the importance of suspecting bacterial pneumonia in patients with N. meningitidis bacteremia, even without meningitis.
Area of Science:
- Infectious Diseases
- Bacteriology
- Pulmonology
Background:
- Neisseria meningitidis is a primary cause of bacterial meningitis globally.
- Meningococcal pneumonia is a less common, yet severe, manifestation of invasive meningococcal disease, occurring in 5-15% of cases.
- While N. meningitidis sepsis and meningitis have high morbidity and mortality, pneumonia is often underreported.
Related Concept Videos
Pneumonia I: Introduction
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Acute Pyelonephritis II: Diagnostic Studies and Management
Pneumonia III: Complications and Assessment
Acute Pyelonephritis I: Introduction
Pneumonia II: Pathophysiology

