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Related Concept Videos

The Bone Matrix01:18

The Bone Matrix

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Bone contains a relatively small number of cells entrenched in a matrix of collagen fibers that provide an adherent surface for inorganic salt crystals. Both components of the matrix, organic and inorganic, contribute to the unusual properties of bone. Without collagen, bones would be brittle and shatter easily. Without mineral crystals, bones would flex and provide little support. This can be observed by an experiment: when the minerals of a bone are dissolved by soaking the bone in...
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Blood Transfusion01:15

Blood Transfusion

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Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
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Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

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Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
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Bone Disorders01:29

Bone Disorders

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Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
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Blood and Nerve Supply to the Bones01:29

Blood and Nerve Supply to the Bones

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Bones are dynamic organs that require a rich supply of oxygen and nutrients. Around 5% to 10% of the cardiac output supplies blood to the bones. A typical long bone has three main sources: the nutrient artery, the metaphyseal and epiphyseal arteries, and the periosteal arteries.
Nutrient Artery
The nutrient artery is the main blood vessel that enters the diaphysis via the nutrient foramen. While most long bones have only one nutrient foramen, large bones, such as the femur, may have two. This...
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Bone Markings01:26

Bone Markings

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Bones have various surface features that help form joints and attach to other soft tissues. Depending on the function, bone markings are categorized into articulating projections, processes for attachment, depressions, and openings.
Articulating Projections
Articulating projections are found where two bones meet to form a joint. These structures are usually found at the ends of bones. The largest articulation is a rounded projection called the head, supported by a narrow neck at the ends of...
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Related Experiment Video

Updated: Dec 14, 2025

Murine Hind Limb Long Bone Dissection and Bone Marrow Isolation
07:17

Murine Hind Limb Long Bone Dissection and Bone Marrow Isolation

Published on: April 14, 2016

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Blood and Bone: The quarantine chronicles.

Kirk A Taylor1, Kellie R Machlus2

  • 1National Heart and Lung Institute Imperial College London London UK.

Research and Practice in Thrombosis and Haemostasis
|July 21, 2020
PubMed
Summary

The Blood and Bone webinar series fostered community and scientific growth during the pandemic. This daily online series successfully connected hematopoiesis and hemostasis/thrombosis researchers globally.

Keywords:
hematopoiesishemostasismegakaryocyteplateletthrombosis

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Related Experiment Videos

Last Updated: Dec 14, 2025

Murine Hind Limb Long Bone Dissection and Bone Marrow Isolation
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Murine Hind Limb Long Bone Dissection and Bone Marrow Isolation

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Homing of Hematopoietic Cells to the Bone Marrow
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Area of Science:

  • Hematology
  • Thrombosis
  • Scientific Communication

Background:

  • The COVID-19 pandemic created a need for virtual scientific exchange.
  • Existing scientific communities sought new platforms for collaboration and knowledge sharing.

Purpose of the Study:

  • To describe the creation and success of the "Blood and Bone" daily webinar series.
  • To highlight the series' role in fostering community and scientific engagement during a global crisis.

Main Methods:

  • A daily online webinar series was established using Zoom and YouTube.
  • A diverse speaker list was curated through community participation.
  • A weekly trainee series was incorporated.

Main Results:

  • The series quickly filled its schedule through September 2020.
  • Daily attendance averaged 200-300 participants, peaking over 600.
  • Sustained engagement was observed for 10 weeks.

Conclusions:

  • The "Blood and Bone" series successfully transformed pandemic-induced chaos into an opportunity for scientific community building.
  • The initiative demonstrated the power of accessible online platforms for global scientific collaboration.