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Updated: Dec 14, 2025

Morphological and Functional Assessment of the Right Ventricle Using 3D Echocardiography
Published on: October 28, 2020
Right ventricular outflow tract obstruction due to a leiomyosarcoma
Nicholas Suraci1, Jason Hoyos1, Diego Baruqui2
1Department of Anesthesia, Mount Sinai Medical Center, Florida, USA.
A rare case of endometrial leiomyosarcoma metastasized to the heart caused significant obstruction. Surgical removal successfully treated this cardiac metastasis, improving patient outcomes.
Area of Science:
- Cardiovascular Medicine
- Oncology
- Pathology
Background:
- Metastatic leiomyosarcoma to the heart is exceptionally rare.
- Endometrial cancer can present with unusual metastatic patterns.
Observation:
- A 65-year-old female presented with dyspnea and weight loss.
- Physical exam revealed a systolic murmur.
- Computed tomography (CT) angiogram showed a mass in the inferior vena cava extending into the right ventricle.
Findings:
- Transesophageal echocardiography confirmed the mass caused right ventricular outflow tract obstruction.
- Surgical excision of the mass was performed.
- Pathology revealed the mass to be endometrial leiomyosarcoma.
Implications:
- This case highlights the importance of considering rare metastatic sites in gynecologic malignancies.
- Multimodality imaging is crucial for diagnosing cardiac masses.
- Surgical intervention can be effective for managing symptomatic cardiac metastases.
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