Related Experiment Video
Updated: Dec 14, 2025

Time-Resolved Fluorescence Anisotropy from Single Molecules for Characterizing Local Flexibility in Biomolecules
Published on: April 25, 2025
Symmetry-induced fluctuation relations for dynamical observables irrespective of their behavior under time reversal
Stefano Marcantoni1,2, Carlos Pérez-Espigares3,4, Juan P Garrahan1,2
1School of Physics & Astronomy, University of Nottingham, Nottingham NG7 2RD, United Kingdom.
Abstract:
We extend previous work to describe a class of fluctuation relations (FRs) that emerge as a consequence of symmetries at the level of stochastic trajectories in Markov chains. We prove that given such a symmetry, and for a suitable dynamical observable, it is always possible to obtain a FR under a biased dynamics corresponding to the so-called generalized Doob transform. The general transformations of the dynamics that we consider go beyond time-reversal or spatial isometries, and an implication is the existence of FRs for observables irrespective of their behavior under time reversal, for example for time-symmetric observables rather than currents. We further show how to deduce in the long-time limit these FRs from the symmetry properties of the generator of the dynamics. We illustrate our results with four examples that highlight the novel features of our work.
Related Concept Videos
Symmetry in Maxwell's Equations
Properties of Fourier series II
A function f(t) is...
Even and Odd Signals
Woodward–Hoffmann Selection Rules and Microscopic Reversibility
Properties of Fourier series I
Oscillations about an Equilibrium Position

