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Updated: Dec 14, 2025

Introduction to Solid Supported Membrane Based Electrophysiology
Published on: May 11, 2013
State-dependent diffusion in a bistable potential: Conditional probabilities and escape rates
Miguel V Moreno1, Daniel G Barci2, Zochil González Arenas3
1Instituto de de Física Teórica, Universidade Estadual Paulista, Rua Dr. Bento Teobaldo Ferraz 271, 01140-070 São Paulo, SP Brazil.
Abstract:
We consider a simple model of a bistable system under the influence of multiplicative noise. We provide a path integral representation of the overdamped Langevin dynamics and compute conditional probabilities and escape rates in the weak noise approximation. The saddle-point solution of the functional integral is given by a diluted gas of instantons and anti-instantons, similar to the additive noise problem. However, in this case, the integration over fluctuations is more involved. We introduce a local time reparametrization that allows its computation in the form of usual Gaussian integrals. We found corrections to the Kramers escape rate produced by the diffusion function which governs the state-dependent diffusion for arbitrary values of the stochastic prescription parameter. Theoretical results are confirmed through numerical simulations.
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