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Methods to Quantify Pharmacologically Induced Alterations in Motor Function in Human Incomplete SCI
Published on: April 18, 2011
Rehabilitation pharmacotherapy: A scoping review
Eiji Kose1, Hidetaka Wakabayashi2
1Department of Pharmacy, Teikyo University School of Medicine University Hospital, Tokyo, Japan.
Polypharmacy, the use of multiple medications, negatively impacts rehabilitation outcomes for older adults. Integrating pharmacotherapy with rehabilitation planning can optimize functional recovery and quality of life.
Area of Science:
- Geriatric Medicine
- Rehabilitation Science
- Clinical Pharmacy
Background:
- Polypharmacy is prevalent in rehabilitation settings, often compromising patient outcomes.
- The interplay between medication regimens and functional recovery in older adults requires careful consideration.
Purpose of the Study:
- To introduce and discuss the concept of rehabilitation pharmacotherapy.
- To highlight the importance of integrating pharmacotherapy and rehabilitation strategies for frail older individuals and those with disabilities.
Main Methods:
- Review of the concept of rehabilitation pharmacotherapy.
- Analysis of the impact of polypharmacy and specific drug classes (e.g., anticholinergics) on rehabilitation outcomes.
- Discussion based on the International Classification of Functioning, Disability, and Health (ICF) framework.
Main Results:
- Polypharmacy and potentially inappropriate medications adversely affect nutritional status and motor function improvement during rehabilitation.
- Anticholinergic drugs are linked to dysphagia, fractures, and impaired cognitive function recovery.
- Tailoring pharmacotherapy to rehabilitation needs and vice versa is crucial.
Conclusions:
- Rehabilitation pharmacotherapy, encompassing "pharmacotherapy in consideration of rehabilitation" and "rehabilitation in consideration of pharmacotherapy," is essential.
- This integrated approach aims to maximize body function, activity, and quality of life for patients undergoing rehabilitation.
- Addressing polypharmacy and drug-specific effects is key to successful rehabilitation outcomes.
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