Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Iterative Synthesis of Pyrene-Coronene Molecular Graphene Nanoribbons.

Angewandte Chemie (International ed. in English)·2026
Same author

A Negatively Curved Pyrene-Fused Azaacene.

Angewandte Chemie (International ed. in English)·2026
Same author

Spatial Analysis of Preoperative Malnutrition: A Geographic Targeting Framework for Nutrition Intervention.

Anesthesiology·2026
Same author

Layer-selective hydrogenation and proton transport in twisted bilayer graphene.

Nature communications·2026
Same author

Mechanistic Insights into Layered Growth of Imine-Linked Bilayer 2D Covalent Organic Frameworks.

Journal of the American Chemical Society·2026
Same author

High Charge Carrier Mobility in Non-Conjugated 3D Covalent Organic Frameworks.

Advanced materials (Deerfield Beach, Fla.)·2026

Related Experiment Video

Updated: Dec 14, 2025

Microscopic Visualization of Porous Nanographenes Synthesized through a Combination of Solution and On-Surface Chemistry
08:18

Microscopic Visualization of Porous Nanographenes Synthesized through a Combination of Solution and On-Surface Chemistry

Published on: March 4, 2021

2.0K

Exploiting the Surface Properties of Graphene for Polymorph Selectivity.

Matthew Boyes1, Adriana Alieva1, Jincheng Tong1

  • 1Department of Chemistry, University of Manchester, Manchester M13 9PL, United Kingdom.

ACS Nano
|July 22, 2020
PubMed
Summary

Graphene templates guide glycine crystallization, favoring the alpha-polymorph. Tunable graphene surface chemistry offers a new route for controlling crystal form and screening polymorphs.

Keywords:
computational modelingcrystallizationglycinegraphenepolymorphismsurface chemistry

More Related Videos

Fabrication of Three-Dimensional Graphene-Based Polyhedrons via Origami-Like Self-Folding
14:52

Fabrication of Three-Dimensional Graphene-Based Polyhedrons via Origami-Like Self-Folding

Published on: September 23, 2018

9.3K
Fabrication of Gate-tunable Graphene Devices for Scanning Tunneling Microscopy Studies with Coulomb Impurities
11:42

Fabrication of Gate-tunable Graphene Devices for Scanning Tunneling Microscopy Studies with Coulomb Impurities

Published on: July 24, 2015

15.9K

Related Experiment Videos

Last Updated: Dec 14, 2025

Microscopic Visualization of Porous Nanographenes Synthesized through a Combination of Solution and On-Surface Chemistry
08:18

Microscopic Visualization of Porous Nanographenes Synthesized through a Combination of Solution and On-Surface Chemistry

Published on: March 4, 2021

2.0K
Fabrication of Three-Dimensional Graphene-Based Polyhedrons via Origami-Like Self-Folding
14:52

Fabrication of Three-Dimensional Graphene-Based Polyhedrons via Origami-Like Self-Folding

Published on: September 23, 2018

9.3K
Fabrication of Gate-tunable Graphene Devices for Scanning Tunneling Microscopy Studies with Coulomb Impurities
11:42

Fabrication of Gate-tunable Graphene Devices for Scanning Tunneling Microscopy Studies with Coulomb Impurities

Published on: July 24, 2015

15.9K

Area of Science:

  • Materials Science
  • Crystallization Science
  • Surface Chemistry

Background:

  • Polymorph control in crystallization remains a significant challenge due to incomplete understanding of nucleation processes.
  • Templated crystallization offers a promising strategy for achieving polymorph selectivity, but template design principles are not well-established.
  • Nanoscale interactions during nucleation require further investigation to guide template design.

Purpose of the Study:

  • To investigate the use of graphene with varying surface chemistry as a template for glycine crystallization.
  • To understand the nanoscale interactions governing polymorph selectivity during templated nucleation.
  • To explore the potential of graphene for selective polymorph crystallization and screening.

Main Methods:

  • Experimental investigation of glycine crystallization on graphene templates with different surface chemistries.
  • Utilizing droplet evaporation techniques to study nucleation at the contact region.
  • Employing computer modeling to elucidate the role of graphene surface chemistry in polymorph stabilization.

Main Results:

  • Graphene templates induce preferential crystallization of the metastable alpha-glycine polymorph over the unstable beta-form.
  • The effect is observed at the contact region of evaporating droplets.
  • Computer modeling suggests that oxidized moieties on the graphene surface stabilize the alpha-polymorph.

Conclusions:

  • Graphene's tunable surface chemistry can be exploited to achieve selective crystallization of specific polymorphs.
  • Graphene emerges as a potential material for polymorph control and high-throughput polymorph screening.
  • Further research into graphene-nucleation interactions can advance the field of controlled crystallization.