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The strange mitochondrial genomes of Metschnikowia yeasts
Dong Kyung Lee1, Tom Hsiang2, Marc-André Lachance1
1Department of Biology, University of Western Ontario, London, ON N6A 1W8, Canada.
Abstract:
While sequencing and characterizing the mitochondrial genomes of 71 strains from the yeast genus Metschnikowia [1] (close cousin to the model species Candida albicans), we uncovered one of the most extreme examples of mitochondrial genome architectural diversity observed to date. These Metschnikowia mitochondrial DNAs (mtDNAs) capture nearly the entire known gene-size and intron-content range for cox1 and cob across all eukaryotic life and show remarkable differences in structure and noncoding content. This genomic variation can be seen both among species and between strains of the same species, raising the question: why are Metschnikowia mitogenomes so malleable?
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