Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Thermosensation01:43

Thermosensation

33.4K
Peripheral thermosensation is the perception of external temperature. A change in temperature (on the surface of the skin and other tissues) is detected by a family of temperature-sensitive ion channels called Transient Receptor Potential, or TRP, receptors. These receptors are located on free nerve endings. Those detecting cold temperatures are closer to the surface of the skin than the nerve endings detecting warmth. These thermoTRP channels, while temperature selective, have relatively...
33.4K
Sensation01:21

Sensation

1.1K
Sensory receptors are specialized neurons that respond to specific types of external stimuli, initiating the process known as sensation. This occurs when sensory input, such as light entering the eye, is detected by these receptors, causing chemical changes in the cells of the retina. These cells then convert the sensory stimulus into action potentials that are transmitted to the central nervous system, a process termed transduction.
Absolute thresholds can quantify the sensitivity of sensory...
1.1K
Sensory Functions of the Skin01:16

Sensory Functions of the Skin

7.5K
The skin is the largest organ of the human body and plays a crucial role in our sensory perception. It contains a vast network of sensory receptors that contribute to the skin's protective function by perceiving physical, biological, and environmental cues and generating relevant responses.
There are two main categories of receptors on the skin: capsulated and non-capsulated. The non-capsulated ones are mainly the pain receptors. The capsulated ones can be further categorized based on the...
7.5K
Introduction to Special Senses01:26

Introduction to Special Senses

7.2K
Sensory receptors play an integral part in comprehending our external and internal environments. They receive diverse stimuli, converting them into the nervous system's electrochemical signals. This conversion occurs as the stimulus alters the sensory neuron's cell membrane potential, instigating the generation of an action potential. This action potential is subsequently transmitted to the central nervous system (CNS), which integrates with other sensory data or higher cognitive...
7.2K
Tactile and Chemical Senses01:27

Tactile and Chemical Senses

574
Tactile senses encompass touch, temperature, and pain, each mediated by specific receptors. Touch receptors detect mechanical energy or pressure against the skin. Sensory fibers from these receptors enter the spinal cord and relay information to the brain stem. Here, most fibers cross over to the opposite side of the brain. The touch information then moves to the thalamus, which projects a map of the body's surface onto the somatosensory areas of the parietal lobes in the cerebral cortex.
574
Somatosensation01:33

Somatosensation

42.7K
The somatosensory system relays sensory information from the skin, mucous membranes, limbs, and joints. Somatosensation is more familiarly known as the sense of touch. A typical somatosensory pathway includes three types of long neurons: primary, secondary, and tertiary. Primary neurons have cell bodies located near the spinal cord in groups of neurons called dorsal root ganglia. The sensory neurons of ganglia innervate designated areas of skin called dermatomes.
42.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A nanoscale atlas of extracellular vesicles and particles in <i>Drosophila</i> olfactory sensilla.

bioRxiv : the preprint server for biology·2026
Same author

Intrinsic Diversity in Odor-Evoked Calcium Rises across <i>Drosophila</i> Olfactory Neurons.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2026
Same author

Morphological specializations of mosquito CO<sub>2</sub>-sensing olfactory receptor neurons.

Proceedings of the National Academy of Sciences of the United States of America·2025
Same author

Simultaneous recording of spikes and calcium signals in odor-evoked responses of <i>Drosophila</i> antennal neurons.

Journal of neurogenetics·2025
Same author

Population-level morphological analysis of paired CO<sub>2</sub>- and odor-sensing olfactory neurons in <i>D. melanogaster</i> via volume electron microscopy.

eLife·2025
Same author

Simultaneous recording of spikes and calcium signals in odor-evoked responses of <i>Drosophila</i> antennal neurons.

bioRxiv : the preprint server for biology·2025
Same journal

Hunting ecology predicts eye arrangements in the modular visual system of spiders.

Current biology : CB·2026
Same journal

Sub-second fluctuations between top-down and bottom-up modes distinguish diverse human brain states.

Current biology : CB·2026
Same journal

Queen bees offload pesticide burden to eggs when social buffering is overwhelmed.

Current biology : CB·2026
Same journal

Pitch selectivity in ferret auditory cortex.

Current biology : CB·2026
Same journal

A cell size-dependent competition between geometry and polarity governs nuclear and spindle positioning in early embryos.

Current biology : CB·2026
Same journal

Trophic cascades drive sustainability in the agricultural heritage rice-fish coculture system.

Current biology : CB·2026
See all related articles

Related Experiment Video

Updated: Dec 14, 2025

A Simple and Inexpensive Method for Determining Cold Sensitivity and Adaptation in Mice
08:35

A Simple and Inexpensive Method for Determining Cold Sensitivity and Adaptation in Mice

Published on: March 17, 2015

15.4K

Neuroscience: Sensing Absolute Cold.

Renny Ng1, Chih-Ying Su1

  • 1Neurobiology Section, Division of Biological Sciences, University of California San Diego, La Jolla, CA, USA.

Current Biology : CB
|July 22, 2020
PubMed
Summary
This summary is machine-generated.

Animals adapt to cold by detecting persistent low temperatures. A new study in Drosophila reveals a neural circuit mechanism that relays cold stimuli to modulate sleep for overwintering.

More Related Videos

Novel Assay for Cold Nociception in Drosophila Larvae
06:52

Novel Assay for Cold Nociception in Drosophila Larvae

Published on: April 3, 2017

8.0K
Method for Simultaneous fMRI/EEG Data Collection during a Focused Attention Suggestion for Differential Thermal Sensation
06:33

Method for Simultaneous fMRI/EEG Data Collection during a Focused Attention Suggestion for Differential Thermal Sensation

Published on: January 5, 2014

12.2K

Related Experiment Videos

Last Updated: Dec 14, 2025

A Simple and Inexpensive Method for Determining Cold Sensitivity and Adaptation in Mice
08:35

A Simple and Inexpensive Method for Determining Cold Sensitivity and Adaptation in Mice

Published on: March 17, 2015

15.4K
Novel Assay for Cold Nociception in Drosophila Larvae
06:52

Novel Assay for Cold Nociception in Drosophila Larvae

Published on: April 3, 2017

8.0K
Method for Simultaneous fMRI/EEG Data Collection during a Focused Attention Suggestion for Differential Thermal Sensation
06:33

Method for Simultaneous fMRI/EEG Data Collection during a Focused Attention Suggestion for Differential Thermal Sensation

Published on: January 5, 2014

12.2K

Area of Science:

  • Neuroscience
  • Animal Behavior
  • Chronobiology

Background:

  • Overwintering requires animals to sense and respond to consistent cold conditions.
  • Behavioral adaptations, such as changes in sleep, are crucial for survival during cold periods.

Purpose of the Study:

  • To elucidate the neural circuit mechanisms underlying the detection and processing of persistent cold stimuli.
  • To understand how these cold signals modulate sleep behavior in preparation for overwintering.

Main Methods:

  • Utilized Drosophila melanogaster as a model organism.
  • Investigated neural pathways from sensory neurons to higher brain centers involved in cold perception.
  • Analyzed the role of specific neural circuits in regulating sleep in response to cold.

Main Results:

  • Identified a circuit mechanism in Drosophila that encodes persistent, absolute cold stimuli.
  • Demonstrated that this circuit relays cold information to higher brain centers.
  • Showed that the cold stimulus modulates sleep patterns.

Conclusions:

  • A defined neural circuit enables Drosophila to sense and process sustained cold temperatures.
  • This sensory-to-central nervous system pathway is critical for modulating sleep, facilitating overwintering survival.