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Using blockchain to log genome dataset access: efficient storage and query.

Gamze Gürsoy1,2, Robert Bjornson3,4, Molly E Green1,2

  • 1Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, 06520, USA.

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|July 23, 2020
PubMed
Summary
This summary is machine-generated.

Blockchain technology offers secure and efficient storage for sensitive genomic data access logs. This approach addresses challenges in data security and querying, with potential applications for other health records.

Keywords:
BlockchainGenomic data access logSecure storage

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Area of Science:

  • Genomics
  • Blockchain Technology
  • Data Security

Background:

  • Genomic variants are sensitive data requiring controlled access.
  • Secure storage and querying of access logs are crucial to prevent misuse.
  • Blockchain technology offers security, immutability, and decentralization for log management.

Purpose of the Study:

  • Develop efficient blockchain-based solutions for logging and querying user activity on genomic datasets.
  • Address challenges of single points of failure in traditional log security.
  • Utilize MultiChain platform for secure data storage and retrieval.

Main Methods:

  • Devised a storage protocol using MultiChain data streams for secure data storage.
  • Created a data frame for efficient querying of blockchain data.
  • Developed an alternate 'bigmem' solution using indices for rapid queries, overcoming memory limitations.

Main Results:

  • The challenge solution queried 100,000 entries in 12 seconds using 120 MB memory, scaling to 470 MB for 600,000 entries.
  • The 'bigmem' solution queried 100,000 entries in 408 seconds using 250 MB memory, scaling to 360 MB for 600,000 entries.
  • Demonstrated efficient storage and querying of genomic access logs using blockchain.

Conclusions:

  • Blockchain technology provides an effective method for storing and querying genomic access logs.
  • The developed protocol can be extended to other sensitive health data, such as electronic health records.
  • The study highlights the potential of blockchain in enhancing genomic data security and accessibility.