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Published on: July 6, 2015
Optimization of femtosecond laser-constructed clear corneal wound sealability for cataract surgery
Étienne Benard-Seguin1, Cristina Bostan, Raphaëlle Fadous
1From the Maisonneuve-Rosemont Hospital Research Center (Benard-Seguin, Sylvestre-Bouchard, de Alwis Weerasekera, Harasymowycz, Brunette), Montreal, Department of Ophthalmology, Université de Montréal (Bostan, Fadous, Sylvestre-Bouchard, Harasymowycz, Brunette), Montreal, Centre de Recherche de l'Institut Universitaire en Santé Mentale de Montréal (Giguère), Montreal, and Clinique Bellevue (Giguère), Montreal, Quebec, Canada.
Purpose:
To compare the sealability of femtosecond laser (FSL)-assisted corneal incisions (CIs) with that of triplanar manual (M)-CIs and to determine FSL wound parameters minimizing leakage.
Setting:
Private practice.
Design:
Phase IV, single-surgeon, retrospective cohort study.
Methods:
One eye per patient was included. Two groups defined by the main wound (FSL-CI or M-CI) were compared for leakage, inferred by placement of a suture at the end of surgery. Leakage in FSL-CIs was analyzed as a function of customizable wound parameters: anterior plane depth (APD), posterior plane depth (PPD), anterior side-cut angle (ASCA), and posterior side-cut angle (PSCA). The risk of leakage of FSL-CIs with optimal and nonoptimal parameters was further compared with that of M-CIs.
Results:
A total of 1100 eyes (757 [68.8%] FSL-CI; 343 [31.2%] M-CI) were included. Wound leakage occurred in 133 FSL-CI (17.6%) and 30 M-CI eyes (8.7%) (P < .001). FSL wound parameters associated with the lowest risk of leakage were 60% APD, 70% PPD, 120 degrees ASCA, and 70 degrees PSCA. FSL-CIs constructed with at least 3 optimal parameters (60% APD, 70% PPD, and 120 degrees ASCA) had a similar risk of leakage to M-CIs (odds ratio [OR], 1.1; 95% CI, 0.5-2.3). FSL-CIs with suboptimal parameters had twice the risk of leakage of M-CIs (OR, 2.0; 95% CI, 1.1-3.8).
Conclusions:
Overall, FSL-CIs leaked more than M-CIs. However, FSL-CIs with optimized wound profiles had an equivalent risk of leakage to M-CIs. Wound parameter customization is an asset of FSL technology that allows optimization of FSL-CI sealability.
