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Updated: Dec 14, 2025

A Protocol for Using Gene Set Enrichment Analysis to Identify the Appropriate Animal Model for Translational Research
Published on: August 16, 2017
Gene Set Analysis: Challenges, Opportunities, and Future Research
Farhad Maleki1, Katie Ovens1, Daniel J Hogan1
1Department of Computer Science, University of Saskatchewan, Saskatoon, SK, Canada.
Abstract:
Gene set analysis methods are widely used to provide insight into high-throughput gene expression data. There are many gene set analysis methods available. These methods rely on various assumptions and have different requirements, strengths and weaknesses. In this paper, we classify gene set analysis methods based on their components, describe the underlying requirements and assumptions for each class, and provide directions for future research in developing and evaluating gene set analysis methods.
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