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Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation.
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The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
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The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
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Update on Pharmacotherapy in Psychodermatological Disorders.

Shrutakirthi D Shenoi1, Savitha Soman2, Ravindra Munoli2

  • 1Department of Dermatology, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Udupi, Karnataka, India.

Indian Dermatology Online Journal
|July 23, 2020
PubMed
Summary
This summary is machine-generated.

Psychodermatology (PD) involves treating skin conditions with psychiatric links using psychotropic medications. This review details antipsychotics, anti-anxiety agents, antidepressants, and miscellaneous drugs for effective PD management.

Keywords:
Anti-anxiety agentsN-acetyl cysteinenaltrexoneanti convulsantsanti psychoticsantidepressantspharmacotherapypsychodermatological disorders

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Area of Science:

  • Dermatology and Psychiatry
  • Psychopharmacology

Background:

  • Psychodermatological (PD) conditions encompass primary psychiatric disorders and secondary psychiatric issues arising from skin diseases.
  • Common PD conditions include delusions of parasitosis, anxiety, and depression.

Purpose of the Study:

  • To review psychotropic medications used in treating psychodermatological conditions.
  • To outline the principles of drug selection and treatment initiation in PD.

Main Methods:

  • A literature search was conducted using PubMed, Google Scholar, and Medline.
  • Articles focusing on the treatment of PD were analyzed.

Main Results:

  • Psychotropic agents include antipsychotics (first- and second-generation), anti-anxiety agents (benzodiazepines, buspirone), antidepressants (SSRIs, SNRIs, NDRIs, TCAs, tetracyclics), and miscellaneous drugs (anticonvulsants, naltrexone, N-acetyl cysteine).
  • Second-generation antipsychotics like risperidone are preferred for delusional infestation over older agents due to a better side-effect profile.
  • Drug selection depends on side-effect profiles, potential drug interactions, and comorbid conditions, with treatment typically starting at low doses and gradually increasing.

Conclusions:

  • Effective psychodermatology treatment requires establishing a psychiatric diagnosis before initiating pharmacotherapy.
  • The choice of psychotropic medication is multifactorial, emphasizing individualized treatment plans.
  • Ongoing research and analysis of treatment options are crucial for optimizing PD care.