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In-vitro Mutagenesis

In-vitro Mutagenesis

To learn more about the function of a gene, researchers can observe what happens when the gene is inactivated or “knocked out,” by creating genetically engineered knockout animals. Knockout mice have been particularly useful as models for human diseases such as cancer, Parkinson’s disease, and diabetes.

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Related Experiment Video

Updated: Dec 14, 2025

A Step-By-Step Method to Detect Neutralizing Antibodies Against AAV using a Colorimetric Cell-Based Assay

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Neutralizing the Neutralizers in AAV Gene Therapy

Roland W Herzog¹, Moanaro Biswas¹

¹Department of Pediatrics, Gene and Cell Therapy Program, Herman B. Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN, USA.

Molecular Therapy : the Journal of the American Society of Gene Therapy

|July 23, 2020

Summary

No abstract available in PubMed .

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