Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation01:30

Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation

631
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
631
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

542
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
542
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

675
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
675
Drugs for Treatment of Constipation-Predominant IBS01:21

Drugs for Treatment of Constipation-Predominant IBS

563
Pharmacological therapies for IBS-C are designed to alleviate abdominal discomfort and enhance bowel function. In patients with IBS-C, fiber supplements may help soften stools and decrease straining, but may also lead to increased gas production and bloating. Osmotic laxatives like milk of magnesia are frequently used to soften stools and increase stool frequency in IBS-C patients. In addition, two drugs approved for use in severe IBS-C adult cases are linaclotide (Linzess) and lubiprostone...
563
Gastrointestinal Motility Disorders01:20

Gastrointestinal Motility Disorders

916
Gastrointestinal or GI motility disorders are characterized by irregular gastrointestinal tract movements, disrupting food transit from the mouth to the anus. They are caused by damage or dysfunction in gut muscles or nerves. These disorders can cause symptoms such as severe constipation, diarrhea, abdominal pain, and swallowing difficulties. Disorders can affect any segment of the GI tract and range widely in severity, from common conditions like GERD to life-threatening conditions like...
916
Irritable Bowel Syndrome III: Medical and Nursing Management01:30

Irritable Bowel Syndrome III: Medical and Nursing Management

560
Managing Irritable Bowel Syndrome (IBS) involves a multifaceted approach, including lifestyle modifications, dietary changes, and medication.
560

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Menstrual-Associated Gastrointestinal Symptoms and Their Impact on IBS Diagnosis in Adolescents.

Neurogastroenterology and motility·2026
Same author

CBT for Pediatric Functional Abdominal Pain: Time to Rethink Traditional Assumptions?

The American journal of gastroenterology·2026
Same author

Knowledge Does Not Translate Into Diagnostic Restraint: Application of Rome-Based IBS Diagnosis Among Medical Students in Latin America.

Neurogastroenterology and motility·2026
Same author

Evaluating linaclotide for the treatment of functional constipation in children and adolescents.

Expert opinion on pharmacotherapy·2026
Same author

American Gastroenterological Association-North American Society for Pediatric Gastroenterology, Hepatology and Nutrition Pediatric Functional Constipation Clinical Care Pathway.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association·2026
Same author

A post hoc analysis of linaclotide in pediatric patients with functional constipation and neurodevelopmental disorders.

Journal of pediatric gastroenterology and nutrition·2026
Same journal

Standardized Mean Differences Reveal Substantial Selection Bias in Post-Reduction Management of Intussusception.

The Journal of pediatrics·2026
Same journal

Parenteral Lipid Dose and Bilirubin Neurotoxicity in Extremely Preterm Infants: A Factorial Randomized Trial.

The Journal of pediatrics·2026
Same journal

Refining Oxygen-Carrying Capacity Metrics in Assessing Mortality Risk from Pneumonia in Children.

The Journal of pediatrics·2026
Same journal

Time-to-Transfer and Hospitalization Duration for Severe Congenital Heart Defects: Implications for Perinatal Regionalization.

The Journal of pediatrics·2026
Same journal

Multimodal neuromonitoring in neonatal hypoxic-ischemic encephalopathy and the association with neurodevelopmental outcomes: A Multicenter Study.

The Journal of pediatrics·2026
Same journal

KP.2-Adapted BNT162b2 COVID-19 Vaccine Uptake and Effectiveness in Children.

The Journal of pediatrics·2026
See all related articles

Related Experiment Video

Updated: Dec 14, 2025

Electroacupuncture Combined with Chinese Medicine Ironing Therapy for Functional Constipation
04:04

Electroacupuncture Combined with Chinese Medicine Ironing Therapy for Functional Constipation

Published on: July 5, 2024

821

Celiac Disease in Children with Functional Constipation: A School-Based Multicity Study.

Amanda C Fifi1, Carlos Velasco-Benitez2, Miguel Saps1

  • 1Department of Pediatrics, University of Miami, Miami, FL.

The Journal of Pediatrics
|July 23, 2020
PubMed
Summary
This summary is machine-generated.

This study found no increased prevalence of celiac disease in Colombian schoolchildren with functional constipation compared to healthy peers. Routine screening for celiac disease in these children is not recommended.

More Related Videos

Implementation of Non-invasive Point of Care Transient Elastography for Evaluation of Liver Disease in Pediatric Populations with Cystic Fibrosis
05:56

Implementation of Non-invasive Point of Care Transient Elastography for Evaluation of Liver Disease in Pediatric Populations with Cystic Fibrosis

Published on: August 29, 2025

361
Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection
07:06

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection

Published on: December 8, 2014

27.5K

Related Experiment Videos

Last Updated: Dec 14, 2025

Electroacupuncture Combined with Chinese Medicine Ironing Therapy for Functional Constipation
04:04

Electroacupuncture Combined with Chinese Medicine Ironing Therapy for Functional Constipation

Published on: July 5, 2024

821
Implementation of Non-invasive Point of Care Transient Elastography for Evaluation of Liver Disease in Pediatric Populations with Cystic Fibrosis
05:56

Implementation of Non-invasive Point of Care Transient Elastography for Evaluation of Liver Disease in Pediatric Populations with Cystic Fibrosis

Published on: August 29, 2025

361
Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection
07:06

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection

Published on: December 8, 2014

27.5K

Area of Science:

  • Pediatric Gastroenterology
  • Gastroenterology
  • Celiac Disease Research

Background:

  • Functional constipation is a common pediatric gastrointestinal disorder.
  • Celiac disease is an autoimmune disorder triggered by gluten consumption.
  • The relationship between functional constipation and celiac disease in children requires further investigation.

Purpose of the Study:

  • To determine if children with functional constipation have a higher prevalence of celiac disease.
  • To assess the need for routine celiac disease screening in children presenting with functional constipation.

Main Methods:

  • A cohort of 1809 schoolchildren in Colombia were screened for functional gastrointestinal disorders (FGIDs).
  • Children with functional constipation were matched with healthy controls.
  • Celiac disease screening involved tissue transglutaminase (tTG)-Immunoglobulin A (IgA) testing, HLA genotyping, and duodenal biopsies for Marsh criteria classification.

Main Results:

  • The overall prevalence of celiac disease in the cohort was 0.6%.
  • One child (0.5%) with functional constipation and three controls (0.7%) were diagnosed with celiac disease.
  • There was no statistically significant difference in celiac disease prevalence between the groups (P = .743).

Conclusions:

  • The prevalence of celiac disease in schoolchildren with functional constipation is similar to that in healthy children.
  • Routine screening for celiac disease in children with functional constipation is not indicated based on these findings.