Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Healthcare Associated Infections II: Preventive Measures01:22

Healthcare Associated Infections II: Preventive Measures

3.5K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
3.5K
Development of Immunocompetence01:22

Development of Immunocompetence

637
The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
637
Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

13.1K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
13.1K
Preventive Healthcare Services01:30

Preventive Healthcare Services

1.7K
Preventive healthcare services keep people healthy via frequent check-ups, screening, and counseling. They primarily aid in disease prevention rather than treating an acute or chronic illness. Preventive treatment also keeps individuals productive and energetic, allowing them to work well into their retirement years. Examples of preventive care services include:
1.7K
Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic01:26

Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic

5.2K
Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
5.2K
Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

Pharmacokinetics in Pediatric Patients: Drug Distribution

176
Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight,...
176

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Arterial ischaemic stroke in adolescents and very young adults-results of a European cohort.

European stroke journal·2026
Same author

Infants' General Movements Were Not Affected by Exposure to Maternal Severe Acute Respiratory Syndrome Coronavirus 2 Infections.

Acta paediatrica (Oslo, Norway : 1992)·2025
Same author

Zeitschrift fur Geburtshilfe und Neonatologie·2025
Same author

Pleura-ABCDE - a structured expert-based protocol for neonatal lung ultrasound documentation and interpretation.

The ultrasound journal·2025
Same author

Recovery from Pediatric Inflammatory Multisystem Syndrome Temporally-Associated with SARS-CoV-2: Follow-Up from a Nationwide German Cohort.

The Journal of pediatrics·2025
Same author

Severity of Pediatric Inflammatory Multisystem Syndrome Temporally Associated with SARS-CoV-2 Diminished During Successive Waves of the COVID-19 Pandemic: Data from a Nationwide German Survey.

The Journal of pediatrics·2024

Related Experiment Video

Updated: Dec 14, 2025

A Murine Model of Group B Streptococcus Vaginal Colonization
10:19

A Murine Model of Group B Streptococcus Vaginal Colonization

Published on: November 16, 2016

14.8K

[Decrease in Group B Streptococcal Infections in Neonates: Analysis of Health Insurance Data 2005 to 2017].

Anna-Lisa Sorg1, Viola Obermeier1, Jakob Armann2

  • 1Institute for Social Pediatrics and Adolescent Medicine, Pediatric Epidemiology, Ludwig Maximilians University Munich, Munich.

Klinische Padiatrie
|July 23, 2020
PubMed
Summary

Group B Streptococcus (GBS) screening in pregnant women is associated with a significant decrease in early-onset sepsis (EOS) risk for newborns. This trend highlights the effectiveness of GBS screening in neonatal care.

More Related Videos

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis
08:46

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis

Published on: August 12, 2020

6.8K
Probiotic Studies in Neonatal Mice Using Gavage
10:36

Probiotic Studies in Neonatal Mice Using Gavage

Published on: January 27, 2019

20.4K

Related Experiment Videos

Last Updated: Dec 14, 2025

A Murine Model of Group B Streptococcus Vaginal Colonization
10:19

A Murine Model of Group B Streptococcus Vaginal Colonization

Published on: November 16, 2016

14.8K
A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis
08:46

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis

Published on: August 12, 2020

6.8K
Probiotic Studies in Neonatal Mice Using Gavage
10:36

Probiotic Studies in Neonatal Mice Using Gavage

Published on: January 27, 2019

20.4K

Area of Science:

  • Neonatal Health
  • Infectious Disease Epidemiology
  • Public Health Policy

Background:

  • German guidelines recommend Group B Streptococcus (GBS) screening for pregnant women to prevent neonatal early-onset sepsis (EOS).
  • GBS screening is not yet a mandatory part of German Maternity Directives.
  • This study investigated the relationship between GBS screening trends and EOS incidence.

Purpose of the Study:

  • To analyze temporal trends in neonatal EOS incidence.
  • To determine the association between GBS screening and EOS risk.
  • To evaluate the impact of GBS screening on neonatal sepsis rates.

Main Methods:

  • Analysis of health insurance data from 313,385 mother-child pairs (2005-2017).
  • GBS infections identified using ICD-10 P36.0; maternal GBS colonization (surrogate for screening) using ICD-10 B95.1.
  • Logistic regression assessed EOS risk trends; Pearson's correlation examined EOS incidence and colonization marker association.

Main Results:

  • Neonatal GBS EOS risk decreased by 9.3% annually (72.0% overall).
  • No significant change in Late Onset Sepsis (LOS) risk was observed.
  • Increased maternal GBS colonization (3.5-fold) correlated inversely with EOS incidence (r=-0.75, p=0.002).

Conclusions:

  • The declining incidence of GBS-related EOS in neonates in Germany is likely linked to increased GBS screening among pregnant women.
  • The stable risk of LOS suggests GBS screening specifically impacts early-onset infections.
  • Findings support the broader implementation of GBS screening in prenatal care.