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Extragastrointestinal stromal tumor presenting as a scrotal mass: First report from India
Qutubuddin Ali1, Krishnanand Anand1, Vishal Bansal1
1Department of General Surgery, L.N. Medical College and J.K. Hospital, Bhopal, India.
Introduction:
Gastrointestinal Stromal Tumours (GIST) are the most common mesenchymal tumours that arises from the wall of the gastrointestinal tract. Similar tumours elsewhere in the abdomen are called extra gastrointestinal stromal tumor (EGIST).
Presentation Of Case:
A 68 years male presented with a gradually enlarging scrotal mass over a period of 6month duration. On examination a mass was felt (5 cm × 4 cm) occupying left side of scrotum and abutting the lower pole of left testis. Left inguinal orchidectomy along with excision of mass was done. HPE revealed a spindle cell pattern with low cellularity and Immunohistochemical analysis revealed the tumor reactive for CD 117 and CD 34 which is suggestive of GIST.
Discussion:
EGIST have been reported in unusual locations, including the pancreas, prostate, and abdominal wall. The occurrence of EGIST is extremely rare and little is known about their actual origin. The diagnosis is by the demonstration of a specific marker CD 117 and CD34. We describe an unusual case of extra gastrointestinal stromal tumor (EGIST) presenting as a primary scrotal mass.
Conclusion:
To the best of our knowledge, this is the first Indian case of an EGIST involving the scrotum as primary site and second such case worldwide.
