Comparison of corneal biomechanical changes after LASIK and F-SMILE with CorVis ST

To evaluate changes in corneal biomechanics after LASIK and F-SMILE.

Elite Eye Center, Tanta, Egypt.

Prospective, randomized, unmasked, interventional comparative case series.

A total of 60 eyes were equally divided into two groups; group A: received LASIK and group B: received F-SMILE. Pentacam and CorVis ST parameters were compared before and 6 months after procedures. P ⩽ 0.05 was used for significance of results.

bIOP decreased by 0.762 ± 1.211 mmHg in group A (p = 0.092), and by 2.52 ± 1.389 mmHg in group B (p < 0.001) and the difference between groups became significant (p = 0.001). A1 increased significantly in group A only (p = 0.036); while A2 decreased insignificantly in both groups. DAR increased significantly in both groups (p < 0.001, p = 0.022), but the difference between groups remained insignificant (p = 0.461). IR increased significantly in group A only (p < 0.001) and the difference between groups became significant (p = 0.026). ARTH decreased in both groups (p = 0.245, p = 0.695) and the difference remained insignificant (p = 0.928). SP-A1 decreased in group A by 8.89 ± 1.38 mmHg/mm (p = 0.637), and by 32.6 ± 4.39 mmHg/mm in group B (p < 0.001) and the postoperative difference between groups was significant (p = 0.013). CBI increased significantly in group A (p < 0.001), but insignificantly in group B (p = 0.098) and postoperative difference between groups was highly significant (p < 0.001). A significant correlation was found between change in CCT and corresponding changes in DAR, IR, and ARTH after surgery in both groups.

The significant differences between groups postoperatively as regards bIOP (p = 0.001), IR (p = 0.026), SP-A1 (p = 0.013), and CBI (p < 0.001) indicate stiffer corneas after F-SMILE and suggest less influence on corneal biomechanics than LASIK.