Related Experiment Video
Updated: Dec 14, 2025

06:41
A New Technique for Quantitative Analysis of Hair Loss in Mice Using Grayscale Analysis
Published on: March 9, 2015
9.3K
Systemic Lupus Erythematosus Presenting as Alopecia Areata
Parnia Forouzan1, Philip R Cohen2
1Dermatology, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, USA.
Cureus
|July 24, 2020
Summary
Alopecia areata, an autoimmune hair loss condition, can indicate underlying systemic lupus erythematosus. Early diagnosis and awareness of associated autoimmune diseases are crucial for comprehensive patient care and treatment.
Area of Science:
- Dermatology
- Rheumatology
- Immunology
Background:
- Alopecia areata is an inflammatory, non-scarring hair loss condition often linked to other autoimmune disorders.
- Common comorbidities include thyroid disorders and vitiligo, but associations with diabetes, psoriasis, rheumatoid arthritis, and systemic lupus erythematosus are also noted.
Observation:
- A 36-year-old woman with alopecia areata showed significant hair regrowth after triamcinolone acetonide injections.
- Further investigations revealed symptoms suggestive of systemic lupus erythematosus.
Findings:
- The patient was diagnosed with systemic lupus erythematosus, highlighting a potential link between alopecia areata and this autoimmune condition.
- Individuals with alopecia areata have an elevated risk of developing systemic lupus erythematosus.
Implications:
- Recognizing alopecia areata may prompt investigation into other autoimmune comorbidities, improving patient outcomes.
- Increased awareness of associated conditions like systemic lupus erythematosus is vital for comprehensive management of alopecia areata patients.
Related Concept Videos
Skin Diseases and Disorders
5.0K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
5.0K
Autoimmune Disorders
1.3K
Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune...
Concept and Mechanism of Autoimmune Diseases
The immune...
1.3K
Accessory Structures of the Skin: Hair Growth and Types
2.1K
Hair growth begins with the production of keratinocytes by the basal cells of the hair bulb. As new cells are deposited at the hair bulb, the hair shaft is pushed through the follicle toward the surface. Keratinization is completed as the cells are pushed to the skin surface to form the shaft of hair that is externally visible. The external hair is completely dead and composed entirely of keratin. Hair can be cut or shaven without damaging the hair structure because the cut is superficial. Most...
2.1K
Skin Cancer
5.6K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
5.6K
Nephrotic Syndrome I : Introduction
370
Nephrotic Syndrome is a chronic kidney disorder defined by clinical findings such as severe proteinuria, hypoalbuminemia, hyperlipidemia, and edema. These symptoms result from damage to the glomeruli, the kidney’s filtering units, increasing their permeability to proteins.Definition and Meaning:Proteinuria, defined as the loss of more than 3.5 grams of protein per day in adults, is a crucial feature of nephrotic syndrome. This condition is often accompanied by edema, the accumulation of...
370
Papillary Dermis
5.2K
Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen...
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen...
5.2K

