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Pleuropulmonary blastoma in an adolescent

Laura V Bownes1, Sara C Hutchins2, Agustin M Cardenas3

  • 1Division of Pediatric Surgery, Department of Surgery, University of Alabama, Birmingham, Birmingham, AL, USA.

Journal of Pediatric Surgery Case Reports
|July 24, 2020
PubMed

Insights

Pleuropulmonary blastoma (PPB) is a rare childhood lung cancer. This report details an unusual case of PPB in a teenage female, highlighting the need for broader diagnostic considerations.

Area of Science:

  • Pediatric Oncology
  • Thoracic Surgery
  • Rare Cancers

Background:

  • Primary pulmonary malignancies are uncommon in pediatric patients.
  • Pleuropulmonary blastoma (PPB) is the most frequent primary lung cancer in children, typically diagnosed before age four.
  • PPB subtypes (I, Ir, II, III) correlate with age at diagnosis and prognosis.

Purpose of the Study:

  • To report an atypical presentation of pleuropulmonary blastoma (PPB).
  • To emphasize the importance of considering rare diagnoses in adolescent patients with persistent respiratory symptoms.

Main Methods:

  • Case report of a teenage female with a one-month history of non-productive cough.
  • Review of diagnostic findings and clinical presentation.

Main Results:

  • The patient, a teenager, was diagnosed with pleuropulmonary blastoma (PPB).
  • This presentation is unusual given the typical age of diagnosis for PPB.

Conclusions:

  • Pleuropulmonary blastoma (PPB) can occur in adolescents, deviating from the typical early childhood diagnosis.
  • Clinicians should consider rare pulmonary malignancies in the differential diagnosis for persistent cough in adolescents.

Keywords:
CancerPediatricPleuropulmonary blastoma

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