Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Psychological and Sociocultural Causes of Schizophrenia01:29

Psychological and Sociocultural Causes of Schizophrenia

363
Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...
363
Schizophrenia01:17

Schizophrenia

589
Schizophrenia, a term introduced by Swiss psychiatrist Eugen Bleuler in 1911, describes a severe psychological disorder marked by profound disruptions in attention, thought processes, language, emotion, and interpersonal relationships. The core feature of schizophrenia is psychosis — a state characterized by a fundamental detachment from reality. This disconnection manifests through distorted logic, impaired perception, and atypical behavior, severely affecting the lives of those...
589
Psychoneuroimmunology: Diabetes and Cancer01:19

Psychoneuroimmunology: Diabetes and Cancer

342
Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
342
Biological Causes of Schizophrenia01:29

Biological Causes of Schizophrenia

362
Schizophrenia, a severe psychiatric disorder, arises from a complex interplay of biological factors, including genetic predisposition, structural brain abnormalities, neurotransmitter dysregulation, and developmental irregularities. These factors collectively contribute to the onset and progression of the disorder, which typically manifests in late adolescence or early adulthood.
Genetic Factors in Schizophrenia
The genetic basis of schizophrenia is strongly supported by family and twin...
362
Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders01:27

Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders

1.6K
Schizophrenia is a neurodevelopmental disorder whose origins are rooted in complex genetic components. Despite our burgeoning understanding, the pathophysiology of this disorder remains incompletely deciphered.
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within...
1.6K
Positive Symptoms Schizophrenia: Hallucinations and Delusions01:26

Positive Symptoms Schizophrenia: Hallucinations and Delusions

315
Schizophrenia is a complex psychiatric disorder characterized by a range of symptoms that significantly impact cognition, behavior, and emotional regulation. Among these, the positive symptoms stand out as they involve the addition or exaggeration of normal mental functions, deviating markedly from typical behavior and perception. Hallucinations and delusions are prominent positive symptoms, each profoundly affecting the individual's experience of reality.
Hallucinations
Hallucinations in...
315

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Two decades of progress in schizophrenia: Evolution, current insights, and future directions.

Spanish journal of psychiatry and mental health·2026
Same author

Clinical correlates and cognitive associations of the neutrophil-to-lymphocyte ratio in first-episode psychosis and at-risk mental states.

Frontiers in psychiatry·2026
Same author

DNA methylation signatures associated with bipolar disorder in peripheral blood improve prediction models.

EBioMedicine·2026
Same author

Perinatal stress as a moderator of the effects of hormonal dysregulation on cognition and symptoms in early psychosis.

Schizophrenia research·2026
Same author

Exposome and cognition in psychosis: an exploratory study in sex-specific patterns in patients and their unaffected siblings.

Schizophrenia research·2026
Same author

Bioenergetic and early treatment response stratification (BIOERES): a two-variable prognostic model for early identification of treatment-resistance schizophrenia.

Translational psychiatry·2026

Related Experiment Video

Updated: Dec 14, 2025

Standardized Data Acquisition for Neuromelanin-Sensitive Magnetic Resonance Imaging of the Substantia Nigra
05:14

Standardized Data Acquisition for Neuromelanin-Sensitive Magnetic Resonance Imaging of the Substantia Nigra

Published on: September 8, 2021

4.3K

Schizophrenia and cancer.

Alexandre González-Rodríguez1, Javier Labad1, Mary V Seeman2

  • 1Department of Mental Health, Parc Tauli University Hospital, Autonomous University of Barcelona (UAB), I3PT, Sabadell, Barcelona. Spain.

Current Opinion in Supportive and Palliative Care
|July 24, 2020
PubMed
Summary

Cancer mortality is higher in individuals with schizophrenia due to patient, provider, and system factors. Addressing these barriers is crucial for improving cancer outcomes in this population.

More Related Videos

Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study
07:30

Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study

Published on: August 18, 2020

7.3K
A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia
05:51

A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia

Published on: June 15, 2011

26.2K

Related Experiment Videos

Last Updated: Dec 14, 2025

Standardized Data Acquisition for Neuromelanin-Sensitive Magnetic Resonance Imaging of the Substantia Nigra
05:14

Standardized Data Acquisition for Neuromelanin-Sensitive Magnetic Resonance Imaging of the Substantia Nigra

Published on: September 8, 2021

4.3K
Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study
07:30

Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study

Published on: August 18, 2020

7.3K
A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia
05:51

A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia

Published on: June 15, 2011

26.2K

Area of Science:

  • Oncology
  • Psychiatry
  • Public Health

Background:

  • Individuals with schizophrenia exhibit higher cancer mortality rates compared to the general population.
  • This disparity highlights significant unmet needs in cancer care for this demographic.

Purpose of the Study:

  • To investigate the multifaceted reasons behind elevated cancer mortality in schizophrenia patients.
  • To identify actionable strategies and solutions for mitigating these risks and improving outcomes.

Main Methods:

  • A comprehensive review of recent scientific literature.
  • Analysis of contributing factors across patient, provider, and health system domains.
  • Examination of barriers to implementing cancer prevention, early detection, and treatment strategies.

Main Results:

  • Identified key reasons for high mortality: patient nonadherence, provider diagnostic overshadowing, and fragmented health systems.
  • Highlighted barriers including poverty, cognitive deficits, stress, stigma, and medication side effects.
  • Noted available strategies for cancer care and examples of successful interdisciplinary collaboration.

Conclusions:

  • High cancer mortality in schizophrenia is an urgent concern requiring multifaceted solutions.
  • Barriers to care are substantial, necessitating innovative approaches.
  • Effective collaboration between mental health and cancer care specialists is vital, alongside robust palliative care for advanced disease.