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Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment
Published on: April 22, 2019
A predictive survival model for patients with head and neck squamous cell carcinoma treated with immune check point
M Bonomi1, P Bhateja1, M Issa1
1Division of Medical Oncology, Ohio State University, Columbus, United States.
Background:
ICIs have expanded treatment options for HNSCC. A minority of the patients respond to these expensive treatments.
Patients And Methods:
This is a single institutional retrospective review on 121 unresectable or metastatic HNSCC patients treated with ICIs. We predicted that inflammatory markers available through routine blood work, in addition to clinical characteristics may divide patients into groups more or less likely to respond to these agents. Here we develop and internally validate our nomogram to predict survival in patients treated with ICIs.
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