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Updated: Dec 14, 2025
Purification and Transplantation of Myogenic Progenitor Cell Derived Exosomes to Improve Cardiac Function in Duchenne Muscular Dystrophic Mice
Published on: April 10, 2019
Exosomal lncRNAs from mesenchymal stem cells as the novel modulators to cardiovascular disease
1Department of Cardiology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230032, China. ayfyhy@126.com.
Aim:
Mesenchymal stem cells (MSCs) have been identified as potential therapeutic candidates for cardiovascular disease (CVD). However, the molecular mechanism underlying their therapeutic effects is unknown.
Findings:
Recently, Chen et al. showed that an exosomal lncRNA derived from MSCs protected against cardiomyocyte apoptosis in vivo, which provided new insight into our understanding of the functions of MSCs. Other exosomal lncRNAs from MSCs have been shown to play pivotal roles in the development of CVD.
Conclusion:
Exosomal lncRNAs are important molecules in the application of MSCs, which reveals, at least in part, the functional mechanism of MSCs.
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01:19Mesenchymal Stem Cells
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