Related Experiment Video
Updated: Dec 14, 2025

Author Spotlight: Investigating the Pathophysiology of Eosinophilic Esophagitis
Published on: May 10, 2024
A 79-year-old man with persistent eosinophilia and elevated immunoglobulin E
Joel P Brooks1, Kaoru Harada1, Nicole K Le1
1From the Department of Internal Medicine, Yale School of Medicine/Yale-New Haven Hospital, New Haven, Connecticut.
Abstract:
The differential diagnoses for eosinophilia include allergic, infectious, autoimmune, and neoplastic diseases. We presented the case of a 79-year-old man with eosinophilia and elevated immunoglobulin E that persisted despite adequate treatment for possible environmental exposures. Further specialized testing based on his initial workup led to his diagnosis. This case highlights the importance of sequential and targeted testing to evaluate for rare causes of eosinophilia.
More Related Videos
Related Concept Videos
Allergic Reactions
Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...

