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Tuberculous Adenitis with Concurrent Hodgkin Lymphoma: A Case Report
Fahmi Yousef Khan1, Antoun Y Kamel1, Mahmoud Khalifa1
1Department of Medicine, Hamad General Hospital, Hamad Medical Corporation, Doha, Qatar.
Oman Medical Journal
|July 25, 2020
Summary
Tuberculous adenitis and Hodgkin lymphoma rarely occur together, presenting similar symptoms like swollen lymph nodes. Early suspicion and diagnosis are crucial for effective treatment and to prevent fatal complications.
Area of Science:
- Oncology
- Infectious Diseases
- Pathology
Background:
- The simultaneous occurrence of tuberculous adenitis and Hodgkin lymphoma is exceptionally rare.
- Both conditions share overlapping clinical manifestations, including lymphadenopathy, fever, weight loss, and night sweats, creating a diagnostic challenge.
Observation:
- A case study involving a 15-year-old girl presenting with cervical lymphadenopathy and fever.
Findings:
- Biopsy of the affected lymph node revealed characteristic Reed-Sternberg cells, indicative of Hodgkin lymphoma.
- Histopathological examination and culture confirmed the presence of acid-fast bacilli, confirming tuberculous adenitis.
- The patient was diagnosed with concurrent tuberculous adenitis and Hodgkin lymphoma within the same lymph node.
Implications:
- This case underscores the importance of maintaining a high index of suspicion for co-existing infections and malignancies.
- Prompt and accurate diagnosis is essential, as overlooking either condition can lead to severe, potentially fatal outcomes.
- Integrated treatment strategies involving anti-tubercular therapy and chemotherapy are vital for managing this dual diagnosis.
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