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Related Concept Videos

Muscle Recovery and Fatigue01:24

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Muscle fatigue refers to the decline in a muscle's ability to maintain the force of contraction after prolonged activity. It primarily stems from changes within muscle fibers. Even before experiencing muscle fatigue, one may feel tired and have the urge to stop the activity. This response, known as central fatigue, occurs due to changes in the central nervous system, namely the brain and spinal cord. While there is no single mechanism that induces fatigue, it may serve as a protective...
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Exercise induces a range of adaptations in muscle tissue, depending on the type and duration of activity. Such physical training can be broadly categorized into two types: endurance exercises and resistance exercises.
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Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
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The contraction strength of muscles is regulated by motor neurons, which modulate the frequency of action potentials dispatched to the motor units based on the body's requirements. This process of varying the muscle stimulation frequency allows muscles to contract with a force that is precisely tailored to the needs of the moment, whether lifting a feather or a heavy box.
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The Use of Thermal Infra-Red Imaging to Detect Delayed Onset Muscle Soreness
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Curcumin Improves Delayed Onset Muscle Soreness and Postexercise Lactate Accumulation.

Alistair R Mallard1,2, David Briskey1,2, Andrew Richards BExSSc1

  • 1RDC Clinical, Brisbane, Australia.

Journal of Dietary Supplements
|July 25, 2020
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Summary

This study found that curcumin, when combined with LipiSperse, improved exercise recovery in healthy males by reducing muscle pain and lactate levels. This enhanced bioavailability may allow for quicker return to training.

Keywords:
curcumindrug delivery systemnutraceuticalrecovery

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Area of Science:

  • Exercise Physiology
  • Nutritional Biochemistry
  • Sports Science

Background:

  • Curcumin's poor bioavailability limits its efficacy, despite known benefits for muscle damage biomarkers.
  • Novel drug delivery systems can enhance curcumin's bioavailability for improved exercise recovery.
  • Understanding curcumin's impact on post-exercise recovery is crucial for athletes and active individuals.

Purpose of the Study:

  • To evaluate the effects of bioavailable curcumin (with LipiSperse) on exercise recovery in recreationally trained males.
  • To assess curcumin's influence on pain perception, inflammation, and muscle damage markers post-exercise.
  • To determine if enhanced curcumin bioavailability can accelerate recovery and potentially increase training intensity.

Main Methods:

  • A randomized, double-blind, placebo-controlled study involving 28 healthy males aged 18-35 years with strength training experience.
  • Participants consumed either curcumin with LipiSperse or a placebo drink before and after lower limb resistance exercise to exhaustion.
  • Assessed pain, thigh circumference, lactate, creatine kinase, and inflammatory markers (hs-CRP, IL-6, IL-10, TNF-alpha) at multiple time points post-exercise.

Main Results:

  • The curcumin group showed significantly less post-exercise capillary lactate compared to the placebo group (7.4 vs 8.8 mmol/L).
  • Muscle pain ratings were lower in the curcumin group at 48 and 72 hours post-exercise compared to placebo.
  • Thigh circumference was reduced in the curcumin group at 24 and 48 hours post-exercise, indicating reduced swelling.

Conclusions:

  • Curcumin supplementation, when formulated with LipiSperse for enhanced bioavailability, may accelerate exercise recovery in healthy males.
  • Reduced muscle pain, modulated inflammatory responses, and decreased lactate accumulation contribute to curcumin's recovery benefits.
  • These findings suggest that bioavailable curcumin could enable a faster return to training or higher training intensities.