[The influence of long-term utilization of some herbicides on oral cavity tissues of white rats]

Three mixtures of herbicides have been administered to white rats of Wistar strain by means of stomach tube. After 9 months of studies laboratory examinations were carried out in these animals namely analysis of urine, peripheral blood, bone marrow smears and segments of parotid glands and cheek's mucous membrane were uptaken to histopathological examinations. Morphological changes whose intensification didn't depend on the dose and type of preparation have been found in the glands. These changes were of non-specific character--similar changes were also present in the glands in rats in the course of poisoning by other toxic agents. Vacuolar changes whose intensification was increasing with the exposure time have been observed in the cells of mucous membrane epithelium.