Related Experiment Video
Updated: Dec 13, 2025

Synthesis of Terpolymers at Mild Temperatures Using Dynamic Sulfur Bonds in PolyS-Divinylbenzene
Published on: May 20, 2019
Hydration of sulfobetaine dizwitterions as a function of alkyl spacer length
Oliver S Hammond1, Leila Moura1, Gaelle Level1
1The QUILL Research Centre, School of Chemistry and Chemical Engineering, Queen's University Belfast, Belfast, BT9 5AG, Northern Ireland, UK. j.holbrey@qub.ac.uk m.blesic@qub.ac.uk.
Abstract:
The solvation and structure of bolaform dizwitterions containing two sulfobetaine moieties in concentrated aqueous solution were determined using neutron diffraction with isotopic substitution (NDIS) combined with modelling of the measured structure factors using Empirical Potential Structure Refinement (EPSR). Strongly directional local hydration was observed in the polar regimes of the dizwitterions with 48-52 water molecules shared between dizwitterion molecules in a first shell water network around each zwitterion pair. Overall, the double zwitterions were highly hydrated, providing experimental evidence in support of the potential formation of protein-resistant hydration layers at zwitterion-water interfaces.
More Related Videos
Related Concept Videos
Regioselectivity and Stereochemistry of Acid-Catalyzed Hydration
Preparation and Reactions of Sulfides
Structure and Nomenclature of Thiols and Sulfides
Solvating Effects
Structure and Physical Properties of Alkynes
In nature, compounds containing both carbon and hydrogen are known as "hydrocarbons". Aliphatic hydrocarbons are compounds whose molecules contain saturated single bonds (i.e., alkanes) or unsaturated double or triple bonds. Alkenes contain carbon–carbon double bonds and have a structural formula CnH2n. Unsaturated hydrocarbons containing carbon–carbon triple bonds are called "alkynes" and are structurally represented by the formula CnH2n-2.
The...
Relative Stabilities of Alkenes

