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A Buchwald-Hartwig Protocol to Enable Rapid Linker Exploration of Cereblon E3-Ligase PROTACs*

Thomas G Hayhow1, Rachel E A Borrows1, Coura R Diène1

  • 1Medicinal Chemistry, Oncology R&D, Research and Early Development, AstraZeneca, Cambridge Science Park, Unit 310 Darwin Building, Cambridge, CB4 0WG, UK.

Chemistry (Weinheim an Der Bergstrasse, Germany)
|July 25, 2020
PubMed

Keywords:
PEPPSIPROTACaminationcereblondrug discovery

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