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Alyssa Breneman1, Julie Hancock2, Chris Breneman3

  • 1Columbia University Vagelos College of Physicians and Surgeons, New York, New York.

Journal of the American Academy of Dermatology
|July 25, 2020
PubMed
Abstract

No abstract available in PubMed .

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Body:In certain scenarios, in vitro dissolution tests can replace in vivo bioequivalence studies. This is particularly true when a drug product, though available in varying strengths, maintains proportional similarity in its active and inactive ingredients. In such cases, the need for in vivo bioequivalence studies for lower strength variants may be waived, provided dissolution tests and in vivo studies on the highest strength yield satisfactory results.Bioequivalence can be indicated through...
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