[Effect of adrenoreceptor blockade on plasma renin activity during postnatal ontogenesis in dogs]

The activity of renin in the blood plasma of 10-, 18--22-day and 2--3-month puppies is higher than in adult dogs. Blocking beta adrenoreceptors in 18--22-day, 2--3 month and adult animals decreases the activity of renin. Hypotensive effect following beta adrenergic block in 10-day puppies and alfa adrenergic block in puppies of all age groups is accompanied by the increase in renin activity. In early ontogenesis, the leading role in regulation of renin secretion belongs to changes in renal hemodynamics.