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Prophylactic intraabdominal drains do not confer benefit in pediatric perforated appendicitis: Results from a quality
Dalya M Ferguson1, K Tinsley Anderson1, Seyed A Arshad1
1Department of Pediatric Surgery, McGovern Medical School at the University of Texas Health Science Center at Houston, 6431 Fannin Street, MSB 5.256, Houston, TX 77030, United States; Center for Surgical Trials and Evidence-based Practice (C-STEP), McGovern Medical School at the University of Texas Health Science Center at Houston, 6431 Fannin Street, MSB 5.256, Houston, TX 77030, United States; Children's Memorial Hermann Hospital, 6411 Fannin Street, Houston, TX 77030, United States.
Insights
Routine prophylactic intraabdominal drains did not reduce intraabdominal abscess (IAA) rates in pediatric perforated appendicitis. The study recommends against their routine use in this patient population.
Area of Science:
- Pediatric Surgery
- Surgical Quality Improvement
- Infectious Disease Prevention
Background:
- Prophylactic intraabdominal drains are utilized to prevent intraabdominal abscess (IAA) following perforated appendicitis.
- The efficacy of routine drain placement in pediatric cases remains a subject of investigation.
Purpose of the Study:
- To evaluate the impact of a quality improvement initiative involving prophylactic intraabdominal drain placement on IAA rates in pediatric perforated appendicitis.
- To determine if routine drain placement reduces the incidence of intraabdominal abscess in children.
Main Methods:
- A 27-month quality improvement initiative involving intraoperative closed-suction drain placement in pediatric patients (<18 years) with perforated appendicitis.
- Comparison of IAA rates between patients who received drains during the initiative and a control group from the preceding and subsequent periods.
- Primary outcome was the 30-day IAA rate, analyzed using univariate and multivariate methods.
Main Results:
- The quality improvement initiative included 270 patients, compared to 109 controls. IAA occurred in 20.0% of initiative patients versus 22.9% of controls (p=0.52).
- Multivariate analysis did not associate the initiative with reduced odds of IAA (OR 0.83, 95% CI 0.48-1.44).
- Median length of stay was longer in the initiative group during the index admission and over 30 postoperative days, though these differences did not persist after adjustment.
Conclusions:
- The quality improvement initiative implementing prophylactic intraabdominal drains did not decrease the intraabdominal abscess rate in pediatric perforated appendicitis.
- Routine prophylactic intraabdominal drain placement is not recommended for pediatric perforated appendicitis based on these findings.
Background/Purpose:
Prophylactic, intraabdominal drains have been used to prevent intraabdominal abscess (IAA) after perforated appendicitis. We hypothesized that routine drain placement would reduce the IAA rate in pediatric perforated appendicitis.
Methods:
A 27-month quality improvement (QI) initiative was conducted: closed-suction, intraabdominal drains were placed intraoperatively in pediatric (age < 18) perforated appendicitis patients. QI patients were compared to controls admitted during the preceding 8 months and following 4 months. The primary outcome was 30-day IAA rate. Univariate and multivariate analyses were performed.
Results:
Two hundred seventy QI patients were compared to 109 controls. There was 100% compliance during 21 of 27 months of the QI initiative; only 7 QI patients did not receive drains. IAA occurred in 20.0% of QI patients and 22.9% of control (p = 0.52). After adjustment, the QI initiative was not associated with reduced odds of IAA (OR 0.83, 95% CI 0.48-1.44). Median length of stay was longer in QI patients during the index admission (p = 0.03) and over 30 postoperative days (p = 0.03), but these relationships did not persist after adjustment.
Conclusions:
A QI initiative investigating prophylactic, intraabdominal drain placement in perforated appendicitis did not reduce the IAA rate. We recommend against routine drain placement in pediatric perforated appendicitis.
Level Of Evidence:
Level III.
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